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420305 | K-252c - CAS 85753-43-1 - Calbiochem

420305
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₁₃N₃O 85753-43-1

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      420305-1MG
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          Glass bottle 1 mg
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          Description
          OverviewA cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (IC50 = 2.45 µM) and protein kinase A (IC50 = 25.7 µM).
          Catalogue Number420305
          Brand Family Calbiochem®
          References
          ReferencesFabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
          Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.
          Product Information
          CAS number85753-43-1
          ATP CompetitiveY
          FormOff-white solid
          Hill FormulaC₂₀H₁₃N₃O
          Chemical formulaC₂₀H₁₃N₃O
          ReversibleY
          Structure formula Image
          Applications
          Biological Information
          Primary TargetPKC
          Primary Target IC<sub>50</sub>2.45 µM against protein kinase C
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          420305

          References

          Reference overview
          Fabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
          Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.

          Brochure

          Title
          PKC Pathway Poster PDF ( 676 KB )
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-April-2011 RFH
          DescriptionA cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase A (IC50 = 25.7 µM) and protein kinase C (IC50 = 2.45 µM).
          FormOff-white solid
          CAS number85753-43-1
          Chemical formulaC₂₀H₁₃N₃O
          Structure formula
          Purity≥95% by HPLC
          SolubilityDMSO (5 mg/ml) or Methanol
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesFabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
          Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.