407951 | Ionomycin, Free Acid, Streptomyces conglobatus in Solution - CAS 56092-81-0 - Calbiochem

407951
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₄₁H₇₂O₉ 56092-81-0

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      407951-1MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Plastic ampoule 1 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          Catalogue Number407951
          Brand Family Calbiochem®
          References
          ReferencesAagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297.
          Takei, N., and Endo, Y. 1994. Brain Res. 652, 65.
          Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
          Lee, H.C. 1993. J. Biol. Chem. 268, 293.
          Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932.
          Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344.
          Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.
          Product Information
          CAS number56092-81-0
          ATP CompetitiveN
          FormClear, colorless to slight yellow solution
          FormulationA 5 mM (1 mg/282 µl) solution of Ionomycin, Free Acid, Streptomyces conglobatus (Cat. No. 407950) in DMSO.
          Hill FormulaC₄₁H₇₂O₉
          Chemical formulaC₄₁H₇₂O₉
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetMobile ion carrier for Ca2+.
          Purity≥90% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped with Blue Ice or with Dry Ice
          Toxicity Irritant
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          407951

          References

          Reference overview
          Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297.
          Takei, N., and Endo, Y. 1994. Brain Res. 652, 65.
          Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
          Lee, H.C. 1993. J. Biol. Chem. 268, 293.
          Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932.
          Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344.
          Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.

          Citations

          Title
        • Jonathan Rios-Doria, et al. (2004) Cleavage of b-catenin by calpain in prostate and mammary tumor cells. Cancer Research 64, 7237-7240.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision01-April-2011 RFH
          DescriptionHighly specific for divalent cations (Ca2+ > Mg2+ >> Sr2+ = Ba2+). More effective than antibiotic A23187 as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5, causing significant absorption in the UV range; however, in contrast to A23187 (Cat. No. 100105), it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes and measurement of cytoplasmic free Ca2+. Induces apoptotic neuronal degeneration in embryonic cortical neurons. Also induces cell cycle arrest in the G1 interval of mature Burkitt lymphoma cell lines.
          FormClear, colorless to slight yellow solution
          FormulationA 5 mM (1 mg/282 µl) solution of Ionomycin, Free Acid, Streptomyces conglobatus (Cat. No. 407950) in DMSO.
          Intert gas (Yes/No) Packaged under inert gas
          CAS number56092-81-0
          Chemical formulaC₄₁H₇₂O₉
          Structure formulaStructure formula
          Purity≥90% by HPLC
          Storage -20°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Irritant
          ReferencesAagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297.
          Takei, N., and Endo, Y. 1994. Brain Res. 652, 65.
          Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
          Lee, H.C. 1993. J. Biol. Chem. 268, 293.
          Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932.
          Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344.
          Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.
          Citation
        • Jonathan Rios-Doria, et al. (2004) Cleavage of b-catenin by calpain in prostate and mammary tumor cells. Cancer Research 64, 7237-7240.