407952 | Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem

407952
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₄₁H₇₀O₉ · Ca 56092-82-1

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      407952-10MG
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          Plastic ampoule 10 mg
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          407952-1MG
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              Plastic ampoule 1 mg
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              407952-25MG
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                  Glass bottle 25 mg
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                  407952-5MG
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                      Glass bottle 5 mg
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                      Description
                      OverviewUseful in cell activation experiments when calcium dose-response data are not required. Also available as a 10 mM solution in DMSO (Cat. No. 407953).
                      Catalogue Number407952
                      Brand Family Calbiochem®
                      References
                      ReferencesDupuy d'Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
                      Lee, H.C. 1993. J. Biol. Chem. 268, 293.
                      Product Information
                      CAS number56092-82-1
                      ATP CompetitiveN
                      FormWhite to off-white solid
                      Hill FormulaC₄₁H₇₀O₉ · Ca
                      Chemical formulaC₄₁H₇₀O₉ · Ca
                      ReversibleN
                      Structure formula ImageStructure formula Image
                      Applications
                      Biological Information
                      Primary TargetUseful in cell activation experiments
                      Purity≥97% by HPLC
                      Physicochemical Information
                      Cell permeableN
                      Dimensions
                      Materials Information
                      Toxicological Information
                      Safety Information according to GHS
                      RTECSNO0650000
                      Safety Information
                      R PhraseR: 22

                      Harmful if swallowed.
                      S PhraseS: 36

                      Wear suitable protective clothing.
                      Product Usage Statements
                      Storage and Shipping Information
                      Ship Code Ambient Temperature Only
                      Toxicity Harmful
                      Storage +2°C to +8°C
                      Protect from Light Protect from light
                      Do not freeze Ok to freeze
                      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 year at 4°C.
                      Packaging Information
                      Packaged under inert gas Packaged under inert gas
                      Transport Information
                      Supplemental Information
                      Specifications

                      Documentation

                      SDS

                      Title

                      Safety Data Sheet (SDS) 

                      Certificates of Analysis

                      TitleLot Number
                      407952

                      References

                      Reference overview
                      Dupuy d'Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
                      Lee, H.C. 1993. J. Biol. Chem. 268, 293.

                      Brochure

                      Title
                      Calcium Metabolism and Related Products Brochure
                      Ionophores Technical Bulletin
                      Data Sheet

                      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                      Revision18-February-2010 RFH
                      DescriptionHighly specific for divalent cations (Ca2+ > Mg2+ >> Sr2+ = Ba2+) and more effective than antibiotic A23187 (Cat. No. 100105) as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5, with intense UV absorption. In contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes. Induces apoptotic neuronal degeneration in embryonic cortical neurons. Also induces cell cycle arrest in the G1 interval of mature Burkitt lymphoma cell lines. Often used in cell activation experiments when calcium dose-response data is not required.
                      FormWhite to off-white solid
                      Intert gas (Yes/No) Packaged under inert gas
                      CAS number56092-82-1
                      RTECSNO0650000
                      Chemical formulaC₄₁H₇₀O₉ · Ca
                      Structure formulaStructure formula
                      Purity≥97% by HPLC
                      SolubilityDMSO (100 mg/ml)
                      Storage +2°C to +8°C
                      Protect from light
                      Do Not Freeze Ok to freeze
                      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 year at 4°C.
                      Toxicity Harmful
                      ReferencesDupuy d'Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
                      Lee, H.C. 1993. J. Biol. Chem. 268, 293.

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                      Catalog Number Description  
                      407950 Ionomycin, Free Acid, Streptomyces conglobatus - CAS 56092-81-0 - Calbiochem Show Pricing & Availability

                      Categories

                      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores