A part of MilliporeSigma

IL031 | Interleukin-2 Protein, Recombinant mouse

20 µg  
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      Replacement Information

      Key Specifications Table

      Key ApplicationsSpeciesPurity
      CULT Mouse Greater than 97% by SDS-PAGE and HPLC analysis.
      Catalogue NumberIL031
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionInterleukin-2 Protein, Recombinant mouse
      OverviewInterleukin-2 (IL-2) is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells. IL031 is a 17.2 kDa protein containing 149 amino acid residues.
      Alternate Names
      • IL-2
      Product Information
      PresentationLyophilized powder from 10 mM NaCitrate 4.0 pH.
      ApplicationThe recombinant nouse Interleukin-2 protein (or IL-2 protein) is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells.
      Key Applications
      • Cell Culture
      Application NotesFor most in vitro applications, IL-2 exerts its biological activity in the concentration range of 0.1 to 1.0 ng/mL.
      Biological Information
      PurityGreater than 97% by SDS-PAGE and HPLC analysis.
      Specific ActivityChemicon's mouse IL-2 is fully biologically active when compared to standards. The ED(50) as determined by the dose-dependent stimulation of mouse CTLL-2 cells is <br /><br /><= 0.2 ng/mL, corresponding to a specific activity of >= 5 x 10(E6) units /mg.
      Entrez Gene SummaryThe protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P60568 # Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells.
      SIZE: 153 amino acids; 17628 Da
      DISEASE:SwissProt: P60568 # A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
      SIMILARITY: SwissProt: P60568 ## Belongs to the IL-2 family.
      Stem Cell Type
      • Hematopoietic Stem Cells
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe lyophilized IL-2, though stable at room temperature, is best stored desiccated at -20°C. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other buffered solutions or stored frozen for future use. Reconstituted IL-2 should be stored in working aliquots at -20°C for up to 6 months.
      Packaging Information
      Material Size20 µg
      Transport Information
      Supplemental Information

      Related Products & Applications

      Product Families


      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors