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407715 | Interleukin-13, Human, Recombinant, E. coli

407715
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      407715-5UG
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      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Glass bottle 5 μg
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          Description
          OverviewRecombinant, human interleukin-13 expressed in E. coli. Pleiotropic cytokine that shares many of the properties of IL-4. Exhibits IL-4-like activities on monocytes/macrophages and human B cells but has no effect on T cells. A potent regulator of STAT6 and JAK3 in NK and T cells. Regulates inflammatory and immune responses. Inhibits inducible nitric oxide synthase in human mesangial cells.
          Catalogue Number407715
          Brand Family Calbiochem®
          SynonymsrhIL-13
          References
          ReferencesYu, C.R., et al. 1998. J. Immunol. 161, 218.
          Saura, M., et al. 1996. Biochem. J. 313, 641.
          Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
          Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
          McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
          Minty, A., et al. 1993. Nature 362, 248.
          Product Information
          CAS number148157-34-0
          FormLyophilized
          FormulationLyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-13.
          Applications
          Biological Information
          Biological activityED₅₀ = 3.0-6.0 ng/ml as measured in a cell proliferation assay using a human factor-dependent cell line, TF-1
          Purity≥97% by SDS-PAGE
          Physicochemical Information
          ContaminantsEndotoxin: <100 pg/µg IL-13
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          407715

          References

          Reference overview
          Yu, C.R., et al. 1998. J. Immunol. 161, 218.
          Saura, M., et al. 1996. Biochem. J. 313, 641.
          Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
          Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
          McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
          Minty, A., et al. 1993. Nature 362, 248.

          Brochure

          Title
          Growth Factors and Cytokines Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision23-July-2008 RFH
          SynonymsrhIL-13
          DescriptionRecombinant, human interleukin-13 expressed in E. coli. Pleiotropic cytokine that shares many of the properties of IL-4. Exhibits IL-4-like activities on monocytes/macrophages and human B cells but has no effect on T cells. Potent regulator of inflammatory and immune responses. Inhibits inducible nitric oxide synthase in human mesangial cells.
          FormLyophilized
          FormulationLyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-13.
          CAS number148157-34-0
          Purity≥97% by SDS-PAGE
          ContaminantsEndotoxin: <100 pg/µg IL-13
          Biological activityED₅₀ = 3.0-6.0 ng/ml as measured in a cell proliferation assay using a human factor-dependent cell line, TF-1
          SolubilityReconstitute to a concentration of ≥5 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
          Toxicity Standard Handling
          ReferencesYu, C.R., et al. 1998. J. Immunol. 161, 218.
          Saura, M., et al. 1996. Biochem. J. 313, 641.
          Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
          Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
          McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
          Minty, A., et al. 1993. Nature 362, 248.