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IL011 | Interleukin-11, recombinant

10 µg  
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      Replacement Information

      Key Specifications Table

      Key ApplicationsSpeciesPurity
      CULT Human Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of IL-11.
      Catalogue NumberIL011
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionInterleukin-11, recombinant
      OverviewInterleukin-11 (IL-11) is a potent lymphoid cell growth factor which stimulates the growth and survivability of certain B-cells and T-cells. Human IL-11 is a 19.1 kDa protein containing 179 amino acid residues.
      Alternate Names
      • IL-11
      Product Information
      PresentationSterile filtered and lyophilized with no additives.
      ApplicationThe recombinant Interleukin-11 protein (or IL-11 protein) is a potent lymphoid cell growth factor which stimulates the growth & survivability of certain B-cells & T-cells.
      Key Applications
      • Cell Culture
      Application NotesFor most in vitro applications, IL-11 exerts its biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): Certain B-cells and T-cells.
      Biological Information
      PurityGreater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of IL-11.
      Specific ActivityThe ED(50) as determined by the dose-dependent stimulation of the proliferation of mouse T11 cells is ≤ 2 ng/mL, corresponding to a specific activity of ≥ 5 x 10<sup>5</sup> units/mg.
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.
      Gene Symbol
      • IL11
      • IL-11
      • oprelvekin
      • Oprelvekin
      • AGIF
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P20809 # Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
      SIZE: 199 amino acids; 21429 Da
      SIMILARITY: SwissProt: P20809 ## Belongs to the IL-6 superfamily.
      Stem Cell Type
      • Hematopoietic Stem Cells
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe lyophilized powder, though stable for a few weeks at room temperature, is best stored at -20°C. After a quick spin, reconstitute in water to a concentration of 0.5-1.0 mg/mL. Please note: This solution is slow to dissolve. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. Reconstituted IL-11 should be stored in undiluted aliquots at -20°C for up to six months.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      RECOMBINANT HUMAN INTERLEUKIN-11 - 2376412 2376412
      RECOMBINANT HUMAN INTERLEUKIN-11 - 2426501 2426501
      RECOMBINANT HUMAN INTERLEUKIN-11 - 2061625 2061625
      RECOMBINANT HUMAN INTERLEUKIN-11 - 2275534 2275534
      RECOMBINANT HUMAN INTERLEUKIN-11 - 2296691 2296691
      RECOMBINANT HUMAN INTERLEUKIN-11 - 2327985 2327985
      RECOMBINANT HUMAN INTERLEUKIN-11 - 2343810 2343810
      RECOMBINANT HUMAN INTERLEUKIN-11 - 2344982 2344982
      RECOMBINANT HUMAN INTERLEUKIN-11 - 2365783 2365783


      Product Selection Guide - Antibodies, small molecule inhibitors, kits, assays and proteins for signaling research.

      Data Sheet

      Interleukin-11, recombinant - Data Sheet

      Related Products & Applications

      Product Families


      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors