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GF007 | Insulin-like Growth Factor-II Protein, Recombinant human

50 µg  
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      Replacement Information

      Key Specifications Table

      Key ApplicationsSpeciesSourcePurity
      CULT Human E.coli Greater than 98% by SDS-PAGE and HPLC analysis
      Catalogue NumberGF007
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionInsulin-like Growth Factor-II Protein, Recombinant human
      OverviewInsulin Like Growth Factor-II (IGF-II) is a polypeptide growth factor which stimulates the proliferation of a wide range of cell types. Human IGF-II is a 7.5 kDa protein containing 67 amino acid residues.
      Alternate Names
      • IGF-II
      Product Information
      PresentationLyophilized powder with no additives
      ApplicationThe Insulin Like Growth Factor-II protein (or IGF-2 protein) is a polypeptide growth factor which stimulates the proliferation of a wide range of cell types.
      Key Applications
      • Cell Culture
      Application NotesFor most in vitro applications, IGF-II exerts its biological activity in the concentration range of 0.5 to 25.0 ng/mL. Responding cells are (partial list): Bone, muscle cells.

      Optimal working dilutions must be determined by end user.

      Optimal working dilutions must be determined by end user.
      Biological Information
      PurityGreater than 98% by SDS-PAGE and HPLC analysis
      Specific ActivityChemicon's Human IGF-II is fully biologically active when compared to standards. The ED50 as determined by a cell proliferation assay using FDC-P1 cells is <= 2.0 ng/mL, corresponding to a specific activity of >= 5 x 105 units/mg.
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is an imprinted gene and is expressed only from the paternally inherited allele. It is a candidate gene for eating disorders. There is a read-through, INS-IGF2, which aligns to this gene at the 3' region and to the upstream INS gene at the 5' region. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
      Gene Symbol
      • IGF2
      • FLJ44734
      • pp9974
      • ORFNames=PP1446
      • C11orf43
      • IGF-II
      • INSIGF
      • Somatomedin-A
      • FLJ22066
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01344 # The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.
      SIZE: 180 amino acids; 20140 Da
      SIMILARITY: SwissProt: P01344 ## Belongs to the insulin family.
      Stem Cell Type
      • Mesenchymal Stem Cells
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe lyophilized IGF-II, though stable at room temperature, is best stored at -20°C. After a quick spin, reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other buffered solutions. Reconstituted IGF-II should be stored in undiluted aliquots at -20°C for up to six months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information

      Related Products & Applications

      Product Families


      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors