506169 InhibitorSelect™ p53 Pathway Regulators Panel

506169
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      506169-1EA
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      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Glass bottle 1 ea
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          Description
          OverviewA panel containing 18 potent, selective and cell-permeable inhibitors and 1 activator that is useful for the study of p53 pathway: 2 mg of ATM Kinase Inhibitor (Cat. No. 118500), 5 mg ATM/ATR Kinase Inhibitor (Cat. No. 118501), 10 mg of Anacardic Acid (Cat. No. 172050), 5 mg of Cdk1 Inhibitor IV, RO-3306 (Cat. No. 217699), 5 mg of Casein Kinase II Inhibitor III, TBCA (Cat. No. 218710), 1 mg of Chk2 Inhibitor II (Cat. No. 220486), 5 mg of Hdm2 E3 Ligase Inhibitor (Cat. No. 373225), 5 mg of JNK Inhibitor II (Cat. No. 420119), 1 mg of MDM2 Antagonist, Nutlin-3, Racemic (Cat. No. 444143), 10 mg of MDMX Inhibitor, SJ-172550 (Cat. No. 444155), 5 mg of MG-132 (Cat. No. 474790), 5 mg of p21-Activated Kinase Inhibitor III, IPA-3 (Cat. No. 506106), 5 mg of Pifithrin-α (Cat. No. 506132), 1 mg of PI-103 (Cat. No. 528100), 1 mg of PARP Inhibitor VIII, PJ34 (Cat. No. 528150), 10 mg of PPM1D Phosphatase Inhibitor (Cat. No. 529578), 10 mg of PRIMA-1 (Cat. No. 530050), 1 mg of Caspase Inhibitor I (Cat. No. 627610), and 1 mg Trichostatin A, Streptomyces sp. (Cat. No. 647925). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817). Supplied with a data sheet.
          Catalogue Number506169
          Brand Family Calbiochem®
          Application Data
          References
          ReferencesFeng, Z. and Levine, A.J., 2010. Trends Cell Biol. 20, 427.
          Wiman, K.G., 2010. Oncogene 29, 4245.
          Brown, C.J., et al. 2009. Nat. Rev. Cancer 9, 862.
          Dey, A., et al. 2008. Br. J. Cancer 98, 4.
          Levine, A.J., et al. 2006. Cell Death Differ. 13, 1027.
          Product Information
          FormSolid
          Hygroscopic Hygroscopic
          Applications
          Biological Information
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 22-36/37/38

          Harmful if swallowed.
          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped with Blue Ice or with Dry Ice
          Toxicity Regulatory Review
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Each solutions is stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          506169

          References

          Reference overview
          Feng, Z. and Levine, A.J., 2010. Trends Cell Biol. 20, 427.
          Wiman, K.G., 2010. Oncogene 29, 4245.
          Brown, C.J., et al. 2009. Nat. Rev. Cancer 9, 862.
          Dey, A., et al. 2008. Br. J. Cancer 98, 4.
          Levine, A.J., et al. 2006. Cell Death Differ. 13, 1027.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision29-Sepmtember-2011 RFH
          Application Data
          DescriptionA panel containing 18 potent, selective and cell-permeable inhibitors and 1 activator that is useful for the study of p53 pathway. The panel contains the following inhibitors/activator and 15 ml anhydrous DMSO for reconstitution:
          FormSolid
          Intert gas (Yes/No) Packaged under inert gas
          SolubilityDMSO (supplied). Please refer to information provided on the CD for reconstitution of individual inhibitors.
          Storage -20°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Each solutions is stable for up to 3 months at -20°C.
          Toxicity Regulatory Review
          ReferencesFeng, Z. and Levine, A.J., 2010. Trends Cell Biol. 20, 427.
          Wiman, K.G., 2010. Oncogene 29, 4245.
          Brown, C.J., et al. 2009. Nat. Rev. Cancer 9, 862.
          Dey, A., et al. 2008. Br. J. Cancer 98, 4.
          Levine, A.J., et al. 2006. Cell Death Differ. 13, 1027.