509281 InSolution™ Leupeptin, Hemisulfate, Microbial - CAS 103476-89-7 - Calbiochem

509281
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₃₈N₆O₄ • 1/2(H2SO4) 103476-89-7

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.09281.0001
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          Glass bottle 10 mg
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          Description
          OverviewThe recommended working range is 10-100 µM for most applications.
          Catalogue Number509281
          Brand Family Calbiochem®
          SynonymsAc-LLR-CHO, 1/2(H2SO4), Ac-Leu-Leu-arginal, hemisulfate
          References
          ReferencesMontenez, J.P., et al. 1994. Toxicol. Lett. 73, 201.
          Sarin, A., et al. 1994. J. Immunol. 153, 862.
          Product Information
          CAS number103476-89-7
          FormLiquid
          FormulationA 50 mM (10 mg/421 µl) sterile-filtered solution of Leupeptin, Hemisulfate, Microbial (Cat. No. 108975) in H₂O.
          Hill FormulaC₂₀H₃₈N₆O₄ • 1/2(H2SO4)
          Chemical formulaC₂₀H₃₈N₆O₄ • 1/2(H2SO4)
          ReversibleY
          Applications
          Biological Information
          Primary Targettrypsin-like proteases and cysteine proteases
          Purity≥90% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide SequenceAc-Leu-Leu-arginal, hemisulfate
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Protect from Light Protect from light
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          References

          Reference overview
          Montenez, J.P., et al. 1994. Toxicol. Lett. 73, 201.
          Sarin, A., et al. 1994. J. Immunol. 153, 862.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision11-April-2014 JSW
          SynonymsAc-LLR-CHO, 1/2(H2SO4), Ac-Leu-Leu-arginal, hemisulfate
          DescriptionA reversible inhibitor of trypsin-like proteases and cysteine proteases. Also known to inhibit activation-induced programmed cell death and to restore defective immune response in HIV+ donors. Often used for the inhibition of endoproteinase Lys-C, kallikrein, papain, plasmin, thrombin, cathepsin B, and trypsin. Leupeptin does not inhibit chymotrypsin, elastase, renin, or pepsin. The recommended working range is 10-100 µM for most applications.
          FormLiquid
          FormulationA 50 mM (10 mg/421 µl) sterile-filtered solution of Leupeptin, Hemisulfate, Microbial (Cat. No. 108975) in H₂O.
          Intert gas (Yes/No) Packaged under inert gas
          CAS number103476-89-7
          Chemical formulaC₂₀H₃₈N₆O₄ • 1/2(H2SO4)
          Peptide SequenceAc-Leu-Leu-arginal, hemisulfate
          Purity≥90% by HPLC
          Storage ≤ -70°C
          Protect from light
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesMontenez, J.P., et al. 1994. Toxicol. Lett. 73, 201.
          Sarin, A., et al. 1994. J. Immunol. 153, 862.