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504776 | InSolution™ Cytochalasin D, Zygosporium mansonii - CAS 22144-77-0 - Calbiochem

504776
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₃₀H₃₇NO₆ 22144-77-0

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.04776.0001
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      Limited AvailabilityLimited Availability
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      Available
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          Glass bottle 1 mg
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          Description
          Catalogue Number504776
          Brand Family Calbiochem®
          SynonymsLygosporin A, Zygosporin A, NSC 209835
          References
          ReferencesSasaki, H., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 2026.
          Blankson, H., et al. 1995. Exp. Cell Res. 218, 522.
          Melamed, I., et al. 1995. Biochem. Biophys. Res. Commun. 209, 1102.
          Verschueren, H., et al. 1995. Eur. J. Cell Biol. 66, 335.
          Aszalos, A., et al. 1994. Cell Immunol. 157, 81.
          Wang, W.H., et al. 1994. Am. J. Physiol. 267, F592.
          Betina, V., and Micekova, D. 1972. Chem. Abstr. 77, 160508q.
          Katagiri, K., and Matsuura, S. 1971. J. Antibiot. 24, 722.
          Product Information
          CAS number22144-77-0
          FormLiquid
          FormulationA 10 mM (1 mg/197 µL) sterile-filtered solution of Cytochalasin D, Zygosporium mansonii (Cat. No. 250255) in DMSO.
          Hill FormulaC₃₀H₃₇NO₆
          Chemical formulaC₃₀H₃₇NO₆
          Hygroscopic Hygroscopic
          ReversibleY
          Structure formula Image
          Applications
          Biological Information
          Primary Targetmicrofilaments
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/38

          Irritating to eyes and skin.
          S PhraseS: 24/25

          Avoid contact with skin and eyes.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Irritant
          Storage ≤ -70°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Sasaki, H., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 2026.
          Blankson, H., et al. 1995. Exp. Cell Res. 218, 522.
          Melamed, I., et al. 1995. Biochem. Biophys. Res. Commun. 209, 1102.
          Verschueren, H., et al. 1995. Eur. J. Cell Biol. 66, 335.
          Aszalos, A., et al. 1994. Cell Immunol. 157, 81.
          Wang, W.H., et al. 1994. Am. J. Physiol. 267, F592.
          Betina, V., and Micekova, D. 1972. Chem. Abstr. 77, 160508q.
          Katagiri, K., and Matsuura, S. 1971. J. Antibiot. 24, 722.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision14-June-2013 JSW
          SynonymsLygosporin A, Zygosporin A, NSC 209835
          DescriptionA cell-permeable fungal toxin that is approximately 10 times more potent than cytochalasin B (Cat. No. 250233) in inhibiting actin filament function. Does not inhibit monosaccharide transport across cell membranes. Inhibits cytoplasmic division by blocking the formation of contractile microfilaments at 10 µM. Inactivates low conductance K+ channels. Also modulates CD4 cross-linking in T lymphocytes and increases intracellular Ca2+ levels. Cytochalasin D also exhibits antibiotic and anti-tumor properties.
          FormLiquid
          FormulationA 10 mM (1 mg/197 µL) sterile-filtered solution of Cytochalasin D, Zygosporium mansonii (Cat. No. 250255) in DMSO.
          Intert gas (Yes/No) Packaged under inert gas
          CAS number22144-77-0
          Chemical formulaC₃₀H₃₇NO₆
          Structure formula
          Purity≥98% by TLC
          Storage ≤ -70°C
          Protect from light
          Hygroscopic
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
          Toxicity Irritant
          ReferencesSasaki, H., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 2026.
          Blankson, H., et al. 1995. Exp. Cell Res. 218, 522.
          Melamed, I., et al. 1995. Biochem. Biophys. Res. Commun. 209, 1102.
          Verschueren, H., et al. 1995. Eur. J. Cell Biol. 66, 335.
          Aszalos, A., et al. 1994. Cell Immunol. 157, 81.
          Wang, W.H., et al. 1994. Am. J. Physiol. 267, F592.
          Betina, V., and Micekova, D. 1972. Chem. Abstr. 77, 160508q.
          Katagiri, K., and Matsuura, S. 1971. J. Antibiot. 24, 722.