377980 | Hispidin - CAS 555-55-5 - Calbiochem

377980
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₃H₁₀O₅ 555-55-5

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      377980-2MG
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          Plastic ampoule 2 mg
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          Description
          OverviewA potent, cell permeable, and reversible inhibitor of protein kinase Cβ isoform (PKCβ; IC50 = 2 µM). Has stronger cytotoxic effects on cancer cells than on normal cells in vitro.
          Catalogue Number377980
          Brand Family Calbiochem®
          Synonyms6-(3,4-Dihydroxystyrl)-4-hydroxy-2-pyrone
          References
          ReferencesGonindard, C., et al. 1997. Cell Biol. Toxicol. 13, 141.
          Product Information
          CAS number555-55-5
          ATP CompetitiveN
          FormYellow powder
          Hill FormulaC₁₃H₁₀O₅
          Chemical formulaC₁₃H₁₀O₅
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetPKCβ
          Primary Target IC<sub>50</sub>2 µM against PKCβ
          Purity≥90% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          377980

          References

          Reference overview
          Gonindard, C., et al. 1997. Cell Biol. Toxicol. 13, 141.

          Brochure

          Title
          PKC Pathway Poster PDF ( 676 KB )
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision11-January-2010 RFH
          Synonyms6-(3,4-Dihydroxystyrl)-4-hydroxy-2-pyrone
          DescriptionA potent, cell permeable, and reversible inhibitor of protein kinase Cβ isoform (PKCβ; IC50 = 2 µM). Has stronger cytotoxic effects on cancer cells than on normal cells in vitro.
          FormYellow powder
          Intert gas (Yes/No) Packaged under inert gas
          CAS number555-55-5
          Chemical formulaC₁₃H₁₀O₅
          Structure formulaStructure formula
          Purity≥90% by HPLC
          SolubilityDMSO (5 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesGonindard, C., et al. 1997. Cell Biol. Toxicol. 13, 141.