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EZHS42 | High Sensitivity Human Amyloid β42 ELISA

EZHS42
96-well plate  
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      Overview

      Replacement Information

      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      Amyloid β42 H ELISA Colorimetric
      Description
      Catalogue NumberEZHS42
      DescriptionHigh Sensitivity Human Amyloid β42 ELISA
      Background InformationAmyloid beta peptides have been implicated in the etiology of Alzheimer’s disease. Amyloid beta 40 is the most prominent peptide and Amyloid beta 42 is the neurotoxic form. The Amyloid beta 42/40-ratio (AB ratio) has been reported as a better indicator of the Alzheimer pathology. Millipore’s High Sensitivity Human Amyloid β42 ELISA kit is used for the measurement of Amyloid β42 in cerebrospinal fluid, cell culture supernatants, primary neurons and plasma in a 96-well format.
      References
      Product Information
      Detection methodColorimetric
      Precision, %
      • Intra-assay <10
      • Inter-assay <10
      Applications
      ApplicationThis High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.
      Key Applications
      • ELISA
      Application NotesThis assay requires 50 µl of sample and is an overnight assay.
      Biological Information
      SpecificityThe Amyloid β42 ELISA (HS) uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-42, which causes a high selectivity for Aβ42. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-40, Aβ1-43 and Aβ1-44.
      Species Reactivity
      • Human
      Analytes Available
      • Amyloid β42
      Gene Symbol
      • APP
      Physicochemical Information
      Sensitivity
      • 8.0 pg/mL (50 µl sample size)
      Linearity of DilutionContact technical support for information
      Standard Curve Range
      • 16 pg/mL – 500 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsComponents in the kit can be stored up to 2 weeks at 2-8°C
      Packaging Information
      Material Size96-well plate
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      References

      Reference overviewPub Med ID
      Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease.
      Katsouri, Loukia, et al.
      Neurobiol. Aging, (2012) 2012

      Show Abstract
      23063647 23063647

      Brochure

      Title
      Immunoassay and Multiplex Kits: Analyte Quarterly Vol. 2 (EMD)
      A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with EMD Millipore Immunoassay Platform Solutions.
      ELISAs, RIAs & GyroMark HT Assays
      Protein Detection Platform and Services Brochure

      Technical Info

      Title
      96 well Template 2 Up
      96 well Template Single
      QUALITY CONTROL RANGES: High Sensitivity Human Amyloid Catalog# EZHS42

      Data Sheet

      Title
      Full Service Custom-built Assays

      Posters

      Title
      Multiplex Assays of Fifteen Human Complement Factors