373402 Hedgehog Antagonist VIII - CAS 330796-24-2 - Calbiochem

373402
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₃H₁₅ClF₄N₄O₂ 330796-24-2

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      373402-5MG
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          Plastic ampoule 5 mg
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          Description
          OverviewA cell-permeable quinazolinyl-urea compound that is shown to potently inhibit OCT-Shh-stimulated Gli transcription activity in a 10t1/2(s12) cell-based Luciferase reporter assay (IC50 = 70 nM).
          Catalogue Number373402
          Brand Family Calbiochem®
          SynonymsHh Signaling Antagonist VIII, 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl)methyl)-urea
          References
          ReferencesBrunton, A.A., et al. 2008. J. Med. Chem. 51, 1108.
          Product Information
          CAS number330796-24-2
          FormClear slightly yellow solid
          Hill FormulaC₂₃H₁₅ClF₄N₄O₂
          Chemical formulaC₂₃H₁₅ClF₄N₄O₂
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Purity≥95% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C0. Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          373402

          References

          Reference overview
          Brunton, A.A., et al. 2008. J. Med. Chem. 51, 1108.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision23-December-2009 RFH
          SynonymsHh Signaling Antagonist VIII, 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl)methyl)-urea
          DescriptionA cell-permeable quinazolinyl-urea compound that is shown to potently inhibit OCT-Shh-stimulated Gli transcription activity in a 10t1/2(s12) cell-based Luciferase reporter assay (IC50 = 70 nM).
          FormClear slightly yellow solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number330796-24-2
          Chemical formulaC₂₃H₁₅ClF₄N₄O₂
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (100 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C0. Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesBrunton, A.A., et al. 2008. J. Med. Chem. 51, 1108.