A part of MilliporeSigma

GF026 | Granulocyte-Macrophage Colony-Stimulating Factor Protein, Recombinant mouse

GF026
20 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Key ApplicationsSpeciesSourcePurity
      CULT Mouse E.coli Greater than 98% by SDS-PAGE and HPLC analysis
      Description
      Catalogue NumberGF026
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionGranulocyte-Macrophage Colony-Stimulating Factor Protein, Recombinant mouse
      OverviewGranulocyte Macrophage Colony Stimulating Factor (GM-CSF) is a potent species specific stimulator of bone marrow cells. GM-CSF stimulated precursor cells of granulocytes, macrophages, and eosinophils. Murine GM-CSF is a 14.0 kDa protein containing 124 amino acid residues.
      Alternate Names
      • GM-CSF
      References
      Product Information
      PresentationSterile filtered solution lyophilized from 10mM HoAc.
      Applications
      ApplicationThe Granulocyte Macrophage Colony Stimulating Factor protein (GM-CSF protein) is a potent species specific stimulator of bone marrow cells.
      Key Applications
      • Cell Culture
      Application NotesFor most in vitro applications, murine GM-CSF exerts its biological activity in the concentration range of 0.05 to 0.5 ng/mL. Responding cells are (partial list): Certain BM precursor cells
      Biological Information
      PurityGreater than 98% by SDS-PAGE and HPLC analysis
      SourceE.coli
      Specific ActivityChemicon's mouse GM-CSF is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent stimulation of the proliferation of mouse FDC-P1 cells in <= 0.2 ng/mL, corresponding to a specific activity of >= 5 x 106 units/mg..
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
      Gene Symbol
      • IL3
      • MGC79399
      • MCGF
      • MULTI-CSF
      • MGC79398
      • IL-3
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P08700 # This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
      SIZE: 152 amino acids; 17233 Da
      SUBUNIT: Monomer.
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Activated T-cells, mast cells, natural killer cells.
      SIMILARITY: SwissProt: P08700 ## Belongs to the IL-3 family.
      Stem Cell Type
      • Hematopoietic Stem Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe lyophilized murine GM-CSF, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute in water to a concentration of 100 ng/uL. This solution can be diluted into other buffered solutions. Reconstituted murine GM-CSF should be stored in working aliquots at -20°C.
      Packaging Information
      Material Size20 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR - 2110478 2110478
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR - 2127770 2127770
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY -2683234 2683234
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY -2716524 2716524
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY -2739386 2739386
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY -2766401 2766401
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY -2767265 2767265
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY -2776259 2776259
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY -2776848 2776848
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY -2794982 2794982
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY -2814894 2814894
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR -2825433 2825433
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR - 2172659 2172659
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR - 2360923 2360923
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR - 2698434 2698434
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR - 2707280 2707280
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR - 2710266 2710266
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY- 2529897 2529897

      Data Sheet

      Title
      RECOMBINANT MOUSE GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR

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      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors