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GF059 | Granulocyte Colony-Stimulating Factor Protein, Recombinant mouse

GF059
10 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      Key ApplicationsSpeciesSourcePurity
      CULT Mouse E.coli Greater than 98% by SDS-PAGE and HPLC analysis.
      Description
      Catalogue NumberGF059
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionGranulocyte Colony-Stimulating Factor Protein, Recombinant mouse
      OverviewGranulocyte Colony Stimulating Factor (G-CSF) is a potent stimulator of bone marrow cells, especially those of neutrophil lineage. In addition G-CSF can enhance the survival and activate the immunological functions of mature neutrophils. GF059 is a 19.0 kDa protein containing 179 amino acid residues.
      Alternate Names
      • G-CSF
      References
      Product Information
      PresentationSterile filtered and lyophilized from 5 mM Na Citrate, pH 4.0. Contains no preservatives.
      Applications
      ApplicationThe Granulocyte Colony Stimulating Factor protein (G-CSF Protein), Recombinant mouse, is a potent stimulator of bone marrow cells, especially those of neutrophil lineage.
      Key Applications
      • Cell Culture
      Biological Information
      PurityGreater than 98% by SDS-PAGE and HPLC analysis.
      SourceE.coli
      Specific ActivityBIOLOGICAL ACTIVITY: <br /><br />GF059 is fully biologically active when compared to standards. The ED(50) as determined by the dose-dependent stimulation of the proliferation of mouse M-NFS-60 cells is <= 1.0 ng/mL, corresponding to a specific activity of >= 2 x 10(E6) units/mg.
      Entrez Gene SummaryThe protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for this gene.
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P09919 # Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
      SIZE: 207 amino acids; 22293 Da
      SUBUNIT: Monomer.
      SUBCELLULAR LOCATION: Secreted.
      PTM: O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).
      SIMILARITY: SwissProt: P09919 ## Belongs to the IL-6 superfamily.
      Stem Cell Type
      • Hematopoietic Stem Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe lyophilized powder, though stable at room temperature, is best stored desiccated at -20°C. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1 mg/mL. This solution can be diluted into other buffered solutions or stored frozen for future use. Reconstituted G-CSF should be stored in undiluted aliquots at 20°C for up to 6 months.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      RECOMBINANT MOUSE GRANULOCYTE -2646981 2646981
      RECOMBINANT MOUSE GRANULOCYTE -2705173 2705173
      RECOMBINANT MOUSE GRANULOCYTE -2751152 2751152
      RECOMBINANT MOUSE GRANULOCYTE -2809821 2809821
      RECOMBINANT MOUSE GRANULOCYTE COLONY STIMULATING FACTOR - 2073609 2073609
      RECOMBINANT MOUSE GRANULOCYTE COLONY STIMULATING FACTOR - 2172730 2172730
      RECOMBINANT MOUSE GRANULOCYTE COLONY STIMULATING FACTOR - 2329141 2329141

      Data Sheet

      Title
      Granulocyte Colony-Stimulating Factor, recombinant mouse - Data Sheet

      Related Products & Applications

      Product Families

      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors