362338 | Glyco-SNAP-1 - Calbiochem

362338
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₁₃H₂₃N₃O₈S

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      362338-5MG
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          Plastic ampoule 5 mg
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          Description
          OverviewA water-soluble nitric oxide (NO) donor. More stable (t½ = 28.5-30.2 hr) than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as cysteine or glutathione.
          Catalogue Number362338
          Brand Family Calbiochem®
          SynonymsN-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
          References
          ReferencesHou, Y., et al. 1999. Methods Enzymol. 301, 242.
          Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett. 6, 2575.
          Product Information
          ATP CompetitiveN
          FormGreen crystalline solid
          Hill FormulaC₁₃H₂₃N₃O₈S
          Chemical formulaC₁₃H₂₃N₃O₈S
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetA water-soluble nitric oxide (NO) donor
          Purity≥96% by NMR
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsUnstable in solution; reconstitute just prior to use.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          362338

          References

          Reference overview
          Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
          Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett. 6, 2575.

          Brochure

          Title
          Nitric Oxide Donors and Scavengers Technical Bulletin
          Nitric Oxide and Oxidative Stress Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision02-July-2008 RFH
          SynonymsN-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
          DescriptionA water-soluble and stable nitric oxide (NO) donor (t½ = 28.5-30.2 hr). Glyco-SNAP-1 is more stable than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8-9). The SNAP moiety acts as an NO group donor and the sugar fragment provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes much more slowly in the presence of thiols such as cysteine or glutathione.
          FormGreen crystalline solid
          Chemical formulaC₁₃H₂₃N₃O₈S
          Structure formulaStructure formula
          Purity≥96% by NMR
          SolubilityH₂O (100 mg/ml), Aqueous Buffers (100 mg/ml), Methanol (5 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsUnstable in solution; reconstitute just prior to use.
          Toxicity Standard Handling
          ReferencesHou, Y., et al. 1999. Methods Enzymol. 301, 242.
          Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett. 6, 2575.