345744 | Ganglioside GT1b, Trisialo, Triammonium Salt, Bovine Brain - Calbiochem

345744
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₉₅H₁₆₂N₅O₄₇ · 3NH₄

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      345744-1MG
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          Plastic ampoule 1 mg
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          Description
          OverviewInhibits Con A-stimulated mitogenesis in murine T cells. Lymphocyte marker in cancer patients. Readily converted to GD1b-disialoganglioside by bacterial and other mammalian neuraminidases without detergent or bile salts.
          M.W. 2180.5 (based on stearoyl - 18:0).
          Catalogue Number345744
          Brand Family Calbiochem®
          SynonymsNeu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄
          References
          ReferencesHakomori, S. 1985. Cancer Res. 45, 2405.
          Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
          Warren, L. 1959. J. Biol. Chem. 234, 1971.
          Product Information
          ATP CompetitiveN
          FormLyophilized
          Hill FormulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
          Chemical formulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetInhibits Con A-stimulated mitogenesis in murine T cells
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          345744

          References

          Reference overview
          Hakomori, S. 1985. Cancer Res. 45, 2405.
          Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
          Warren, L. 1959. J. Biol. Chem. 234, 1971.

          Brochure

          Title
          Gangliosides Technical Bulletin
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-July-2009 JSW
          SynonymsNeu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄
          DescriptionTrisialoganglioside prepared from bovine gray matter. Readily converted to GD1b-disialoganglioside by bacterial and mammalian sialidases without detergent or bile salts. Inhibits mitogenesis in concanavalin A-stimulated murine T-cells. Lymphocyte marker in cancer patients.

          Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
          FormLyophilized
          Chemical formulaC₉₅H₁₆₂N₅O₄₇ · 3NH₄
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityEthanol or Methanol. For use in aqueous systems, dissolve in a small amount of ethanol and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions can be filter sterilized.
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.
          Toxicity Irritant
          ReferencesHakomori, S. 1985. Cancer Res. 45, 2405.
          Momoi, T., et al. 1976. Biochim. Biophys. Acta 441, 488.
          Warren, L. 1959. J. Biol. Chem. 234, 1971.