505311 | Gallamine Triethiodide - CAS 65-29-2 - Calbiochem

505311
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₃₀H₆₀I₃N₃O₃ 65-29-2

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      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05311.0001
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          Glass bottle 5 gm
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          Description
          OverviewA negative allosteric modulator selective for muscarinic AChRs. Most selective for M2 receptors (Ki = 2.4 nM) over other mAChRs (M2 > M1 = M4 > M3 = M5). Used to study the roles of M2 receptors in neuromuscular transmission and neuroimmunology.
          Catalogue Number505311
          Brand Family Calbiochem®
          Synonyms2,2ʹ,2ʹʹ-(benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethanaminium) iodide, Muscarinic Receptor Antagonist, Gallamine Triethiodide, Muscarinic mAChR Antagonist, Gallamine Triethiodide
          References
          ReferencesBeltrame, P., 2011. Clin. Exp. Immunol. 164, 170.
          Gnagey, A., et al., 1999. Mol. Pharmacol. 56, 1245.
          Leppik, A., et al. 1994. Mol. Pharmacol. 45, 983.
          Burke, E., 1986. Mol. Pharmacol. 30, 58.
          Product Information
          CAS number65-29-2
          FormWhite powder
          Hill FormulaC₃₀H₆₀I₃N₃O₃
          Chemical formulaC₃₀H₆₀I₃N₃O₃
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetmAChR
          Primary Target K<sub>i</sub>2.4 nM
          Purity≥98% by TLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Beltrame, P., 2011. Clin. Exp. Immunol. 164, 170.
          Gnagey, A., et al., 1999. Mol. Pharmacol. 56, 1245.
          Leppik, A., et al. 1994. Mol. Pharmacol. 45, 983.
          Burke, E., 1986. Mol. Pharmacol. 30, 58.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision17-July-2013 JSW
          Synonyms2,2ʹ,2ʹʹ-(benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethanaminium) iodide, Muscarinic Receptor Antagonist, Gallamine Triethiodide, Muscarinic mAChR Antagonist, Gallamine Triethiodide
          DescriptionA negative allosteric modulator selective for muscarinic AChRs. Most selective for M2 receptors (Ki = 2.4 nM) over other mAChRs (M2 > M1 = M4 > M3 = M5). Used to study the roles of M2 receptors in neuromuscular transmission and neuroimmunology.
          FormWhite powder
          CAS number65-29-2
          Chemical formulaC₃₀H₆₀I₃N₃O₃
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityH₂O (100 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesBeltrame, P., 2011. Clin. Exp. Immunol. 164, 170.
          Gnagey, A., et al., 1999. Mol. Pharmacol. 56, 1245.
          Leppik, A., et al. 1994. Mol. Pharmacol. 45, 983.
          Burke, E., 1986. Mol. Pharmacol. 30, 58.