345831 Galectin-1, Human, Recombinant, E. coli

345831
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      Overview

      Replacement Information

      Key Specifications Table

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      345831-50UG
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          Plastic ampoule 50 μg
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          Description
          OverviewRecombinant, human galectin-1 expressed in E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.
          Catalogue Number345831
          Brand Family Calbiochem®
          SynonymsLactose-binding lectin 1, Beta-galactoside-binding lectin L-14-I, S-Lac lectin 1, Galaptin, 14 kDa lectin, HPL, HBL, MAPK activating protein MP12
          References
          ReferencesRabinovich, A., et al. 2002. Trends Immunol. 23, 313.
          Rabinovich, A., et al. 2002. J. Leukoc. Biol. 71, 741.
          Hughes, R.C., et al. 2001. Biochimie. 83, 667.
          Product Information
          FormSolid
          FormulationLyophilized from sterile-filtered 20 mM Tris-HCl, pH 7.5.
          Applications
          Biological Information
          Purity≥98% by SDS-PAGE
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Diluted working solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          345831

          References

          Reference overview
          Rabinovich, A., et al. 2002. Trends Immunol. 23, 313.
          Rabinovich, A., et al. 2002. J. Leukoc. Biol. 71, 741.
          Hughes, R.C., et al. 2001. Biochimie. 83, 667.

          Brochure

          Title
          Biologics 32.3 PDF ( 927 KB )
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-June-2008 RFH
          SynonymsLactose-binding lectin 1, Beta-galactoside-binding lectin L-14-I, S-Lac lectin 1, Galaptin, 14 kDa lectin, HPL, HBL, MAPK activating protein MP12
          DescriptionRecombinant human galectin-1 expressed in and purified from E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.
          FormSolid
          FormulationLyophilized from sterile-filtered 20 mM Tris-HCl, pH 7.5.
          Purity≥98% by SDS-PAGE
          SolubilityH₂O (0.1-1 mg/ml). Further dilute into aqueous buffers as needed.
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Diluted working solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
          Toxicity Standard Handling
          ReferencesRabinovich, A., et al. 2002. Trends Immunol. 23, 313.
          Rabinovich, A., et al. 2002. J. Leukoc. Biol. 71, 741.
          Hughes, R.C., et al. 2001. Biochimie. 83, 667.