345670 | Galanthamine, Hydrobromide - CAS 69353-21-5 - Calbiochem

345670
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₇H₂₁NO₃ · HBr 69353-21-5

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      345670-20MG
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          20 mg
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          Description
          OverviewA competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.
          Catalogue Number345670
          Brand Family Calbiochem®
          SynonymsNivalin, HBr
          References
          ReferencesPilger, C., et al. 2001. J. Mol. Graph. Model 19, 288.
          Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297.
          Southan, G.J., et al. 1996. Br. J. Pharmacol. 117, 619.
          Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.
          Product Information
          CAS number69353-21-5
          ATP CompetitiveY
          FormWhite solid
          Hill FormulaC₁₇H₂₁NO₃ · HBr
          Chemical formulaC₁₇H₂₁NO₃ · HBr
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetAcetylcholinesterase
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSDF8075000
          Safety Information
          R PhraseR: 25

          Toxic if swallowed.
          S PhraseS: 22-36/37/39-45

          Do not breathe dust.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          345670

          References

          Reference overview
          Pilger, C., et al. 2001. J. Mol. Graph. Model 19, 288.
          Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297.
          Southan, G.J., et al. 1996. Br. J. Pharmacol. 117, 619.
          Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.

          Brochure

          Title
          Alzheimer's Disease Brochure & Technical Guide
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision30-March-2010 RFH
          SynonymsNivalin, HBr
          DescriptionCholinesterase antagonist. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats.
          FormWhite solid
          CAS number69353-21-5
          RTECSDF8075000
          Chemical formulaC₁₇H₂₁NO₃ · HBr
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (5 mg/ml), Ethanol (1 mg/ml) or H₂O (1 mg/ml)
          Storage +2°C to +8°C
          Protect from moisture
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Toxic
          Merck USA index14, 4340
          ReferencesPilger, C., et al. 2001. J. Mol. Graph. Model 19, 288.
          Iliev, A., et al. 1999. Methods Find. Exp. Clin. Pharmacol. 21, 297.
          Southan, G.J., et al. 1996. Br. J. Pharmacol. 117, 619.
          Mutafova-Yambolieva, V.N., et al. 1993. Gen. Pharmacol. 24, 1253.