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14-715 | GRK6 Protein, active, 10 µg

14-715
10 µg  
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      Overview

      Replacement Information
      Description
      Catalogue Number14-715
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionGRK6 Protein, active, 10 µg
      OverviewN-terminal 6His-tagged, recombinant, full length human GRK6

      G protein coupled receptor kinase
      References
      Product Information
      Applications
      ApplicationActive, N-terminal 6His-tagged, recombinant, full length human GRK6. For use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene.
      Gene Symbol
      • GRK6
      • FLJ32135
      • GPRK6
      Protein TargetGRK6
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyAGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P43250 # Specifically phosphorylates the activated forms of G protein-coupled receptors.
      SIZE: 576 amino acids; 65991 Da
      SUBCELLULAR LOCATION: Membrane; Lipid-anchor.
      TISSUE SPECIFICITY: Widely expressed.
      PTM: It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.
      SIMILARITY: SwissProt: P43250 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 RGS domain.
      Molecular Weight69.8kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of casein
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C from date of shipment
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications

      Related Products & Applications

      Alternative Packsize

      Catalog Number Description  
      14-715M GRK6 Protein, active, 250 µg Show Pricing & Availability

      Accessories

      Catalog Number Description  
      20-109 Protein Dilution Buffer B+ Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases
      Life Science Research > Proteins and Enzymes > Purified Kinases