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14-714 | GRK5 Protein, active, 10 µg

10 µg  
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      Replacement Information
      Catalogue Number14-714
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionGRK5 Protein, active, 10 µg
      OverviewN-terminal 6His-tagged, recombinant, full length, human GRK5
      Product Information
      ApplicationActive, N-terminal 6His-tagged, recombinant, full length, human GRK5, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).
      Gene Symbol
      • GRK5
      • GPRK5
      Protein TargetGRK5
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyAGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P34947 # Specifically phosphorylates the activated forms of G protein-coupled receptors.
      SIZE: 590 amino acids; 67787 Da
      TISSUE SPECIFICITY: Highest levels in heart, placenta, lung > skeletal muscle > brain, liver, pancreas > kidney.
      SIMILARITY: SwissProt: P34947 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 RGS domain.
      Molecular Weight71.6kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of casein
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C from date of shipment
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information

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      Alternative Packsize

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      Product Families


      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases
      Life Science Research > Proteins and Enzymes > Purified Kinases