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344215 | Formononetin - CAS 485-72-3 - Calbiochem

344215
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₆H₁₂O₄ 485-72-3

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      344215-5MG
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          Glass bottle 5 mg
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          Description
          OverviewA phytoestrogenic isoflavone found in soy-based foods. Displays potent antioxidant properties and acts as a selective inhibitor of the γ-isoform of alcohol dehydrogenase. Shown to interact with human estrogen receptors with low potency. Induces mammary gland proliferation in mice.
          Catalogue Number344215
          Brand Family Calbiochem®
          Synonyms7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one
          References
          ReferencesPool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
          Toda, S., and Shirataki, Y. 1999. Phytother. Res. 13, 163.
          Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res. 26, 63.
          Keung, W.M. 1995. Biochem. Biophys. Res. Commun. 215, 1137.
          Wang, W., et al. 1995. Nutr. Cancer 23, 131.
          Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol. 49, 153.
          Product Information
          CAS number485-72-3
          ATP CompetitiveN
          FormOff-white solid
          Hill FormulaC₁₆H₁₂O₄
          Chemical formulaC₁₆H₁₂O₄
          ReversibleN
          Structure formula Image
          Applications
          Biological Information
          Primary TargetSelective inhibitor of the γ-isoform of alcohol dehydrogenase
          Purity≥90% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          344215

          References

          Reference overview
          Pool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
          Toda, S., and Shirataki, Y. 1999. Phytother. Res. 13, 163.
          Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res. 26, 63.
          Keung, W.M. 1995. Biochem. Biophys. Res. Commun. 215, 1137.
          Wang, W., et al. 1995. Nutr. Cancer 23, 131.
          Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol. 49, 153.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision08-April-2011 RFH
          Synonyms7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one
          DescriptionA non-steroidal phytoestrogenic isoflavone found in soy-based food products. Has been shown to interact with human estrogen receptor with relatively low potency. Induces mammary gland proliferation in mice. Inhibits lecithin peroxidation induced by hydroxyl radicals. Also acts as a selective inhibitor of γ-isoform of alcohol dehydrogenase.
          FormOff-white solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number485-72-3
          Chemical formulaC₁₆H₁₂O₄
          Structure formula
          Purity≥90% by HPLC
          SolubilityDMSO (200 mg/ml) or Methanol (2 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.
          Toxicity Irritant
          Merck USA index14, 4244
          ReferencesPool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
          Toda, S., and Shirataki, Y. 1999. Phytother. Res. 13, 163.
          Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res. 26, 63.
          Keung, W.M. 1995. Biochem. Biophys. Res. Commun. 215, 1137.
          Wang, W., et al. 1995. Nutr. Cancer 23, 131.
          Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol. 49, 153.