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341576 | Fibrinogen, Human Plasma

341576
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      341576-100MG
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          Glass bottle 100 mg
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          341576-1GM
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              Glass bottle 1 gm
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              Description
              OverviewNative fibrinogen from human plasma. A plasma glycoprotein, essential for clotting of blood, synthesized and secreted by hepatic parenchymal cells. Contains ≥ 90% clottable proteins.
              Do not disturb until the fibrinogen is completely solubilized.
              Catalogue Number341576
              Brand Family Calbiochem®
              SynonymsCoagulation Factor I
              References
              Product Information
              CAS number9001-32-5
              FormLyophilized
              FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
              Applications
              ApplicationFibrinogen, CAS 9001-32-5 , is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains >90% clottable protein.
              Biological Information
              Biological activityContains ≥90% clottable proteins.
              Purityhomogeneous by SDS-PAGE.
              SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              R PhraseR: 20/21/22

              Harmful by inhalation, in contact with skin and if swallowed.
              S PhraseS: 36

              Wear suitable protective clothing.
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Harmful
              Storage +2°C to +8°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Do not store solutions on ice; precipitation will occur. Stock solutions are stable for up to 6 months at -70°C. Avoid freeze-thaw cycles.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              341576

              Brochure

              Title
              Coagulation Factors Technical Bulletin
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision27-September-2007 RFH
              SynonymsCoagulation Factor I
              DescriptionNative fibrinogen from human plasma. A plasma glycoprotein, essential for clotting blood. Synthesized and secreted by hepatic parenchymal cells. Fibrinogen, also known as Coagulation Factor I, is an acute-phase plasma protein found at a concentration of about 300 mg/100 ml. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is found at elevated levels during pregnancy, after surgical trauma, or in cases of myocardial infarction, and is decreased in cases of liver cirrhosis and serum hepatitis.
              FormLyophilized
              FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
              SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
              CAS number9001-32-5
              Purityhomogeneous by SDS-PAGE.
              Biological activityContains ≥90% clottable proteins.
              SolubilitySterile distilled H₂O. Protein must be thawed in a 37°C water bath. Solutions used to reconstitute fibrinogen should first be brought to 37°C. Once at 37°C, the solution can be added to the fibrinogen and this mixture should remain at 37°C until the fibrinogen is completely solubilized. If the vial is disturbed before the fibrinogen is completely dissolved, the fibrinogen will precipitate. Please see vial label for lot-specific reconstitution volume.
              Storage +2°C to +8°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Do not store solutions on ice; precipitation will occur. Stock solutions are stable for up to 6 months at -70°C. Avoid freeze-thaw cycles.
              Toxicity Harmful
              Merck USA index14, 4071