14-473 | Fes/Fps Protein, active, 10 µg

14-473
10 µg  Also available in 250 µg size --call for pricing and availability and reference catalog number 14-473M when ordering the 250 µg size.
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      Overview

      Replacement Information
      Description
      Catalogue Number14-473
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionFes/Fps Protein, active, 10 µg
      OverviewRecombinant full length human Fes, containing an N-terminal His6-tag
      References
      Product Information
      Applications
      ApplicationActive, recombinant full length human Fes, containing an N-terminal His6-tag, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceExpressed by baculovirus in Sf21 insect cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.
      Gene Symbol
      • FES
      • FPS
      • C-Fes
      Protein TargetFes/Fps
      Purification MethodNi-NTA agarose
      Target Sub-FamilyTK
      UniProt Number
      UniProt SummarySIZE: 822 amino acids; 93497 Da
      SIMILARITY: SwissProt: P07332 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. & Contains 1 FCH domain. & Contains 1 protein kinase domain. & Contains 1 SH2 domain.
      Molecular Weight98kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of the Poly (Glu4-Tyr) (4:1) substrate
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -70C
      Packaging Information
      Material Size10 µg
      Material PackageAlso available in 250 µg size --call for pricing and availability and reference catalog number 14-473M when ordering the 250 µg size.
      Transport Information
      Supplemental Information
      Specifications

      Related Products & Applications

      Alternative Packsize

      Catalog Number Description  
      14-473M Fes/Fps Protein, active, 250 µg Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases
      Life Science Research > Proteins and Enzymes > Purified Kinases