505483 FFN511 - CAS 1004548-96-2 - Calbiochem

505483
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₇H₂₀N₂O₂ 1004548-96-2

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      5.05483.0001
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          Glass bottle 1 mg
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          Description
          OverviewA fluorescent false neurotransmitter that acts as an optical tracer that inhibits serotonin binding to VMAT2-containing membranes (IC50 = 1 µM). Compound has been used to assess the functional status of TH positive neurons by fluorescent measurement of uptatke and release.
          Catalogue Number505483
          Brand Family Calbiochem®
          SynonymsFluorescent False Neurotransmitter 511, Vesicle Monoamine Transporter (VMAT2) Substrate, FFN511
          References
          ReferencesDulcis, D. et al. 2013. Science 340, 449.
          Gubernator, N. G. et al. 2009. Science 324, 1441.
          Product Information
          CAS number1004548-96-2
          FormYellow solid
          Hill FormulaC₁₇H₂₀N₂O₂
          Chemical formulaC₁₇H₂₀N₂O₂
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetVMAT2
          Primary Target IC<sub>50</sub>1 µ
          Purity≥99% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          References

          Reference overview
          Dulcis, D. et al. 2013. Science 340, 449.
          Gubernator, N. G. et al. 2009. Science 324, 1441.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-September-2013 JSW
          SynonymsFluorescent False Neurotransmitter 511, Vesicle Monoamine Transporter (VMAT2) Substrate, FFN511
          DescriptionA fluorescent false neurotransmitter that acts as an optical tracer that inhibits serotonin binding to VMAT2-containing membranes (IC50 = 1 µM). Compound has been used to assess the functional status of TH positive neurons by fluorescent measurement of uptatke and release.
          FormYellow solid
          CAS number1004548-96-2
          Chemical formulaC₁₇H₂₀N₂O₂
          Structure formulaStructure formula
          Purity≥99% by HPLC
          SolubilityDMSO (5 mM)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesDulcis, D. et al. 2013. Science 340, 449.
          Gubernator, N. G. et al. 2009. Science 324, 1441.