341215 | Exotoxin A, Pseudomonas aeruginosa - CAS 91262-95-2 - Calbiochem

341215
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #
      91262-95-2

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      341215-1MG
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          Alu drum 1 mg
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          Description
          OverviewShown to inhibit protein synthesis through ADP-ribosylation of elongation factor 2. Cytopathic for a number of cell lines and exhibits toxicity in animals. Has enzymatic activity identical to that of diphtheria toxin, however it has distinct target-cell specificities and is immunologically unrelated.
          Catalogue Number341215
          Brand Family Calbiochem®
          References
          ReferencesPrentice, G.A., and Merrill, A.R. 1999. Anal. Biochem. 272, 216.
          Product Information
          CAS number91262-95-2
          ATP CompetitiveN
          FormLyophilized
          FormulationSolid lyophilized from 150 mM NaCl, 10 mM sodium phosphate buffer, pH 7.5.
          ReversibleN
          Applications
          ApplicationExotoxin A, Pseudomonas aeruginosa, CAS 91262-95-2, inhibits protein synthesis through ADP-ribosylation of elongation factor 2. Shown to be cytopathic for a number of cell lines.
          Biological Information
          Primary TargetADP-ribosylation of elongation factor 2
          PuritySingle band by SDS-PAGE; single precipitin band by immunodiffusion
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSLF2991000
          Safety Information
          R PhraseR: 26/27/28

          Very toxic by inhalation, in contact with skin and if swallowed.
          S PhraseS: 22-36/37/39-45

          Do not breathe dust.
          Wear suitable protective clothing, gloves and eye/face protection.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Highly Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +2°C to +8°C
          Do not freeze Yes
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.
          Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          341215

          References

          Reference overview
          Prentice, G.A., and Merrill, A.R. 1999. Anal. Biochem. 272, 216.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision24-June-2008 RFH
          DescriptionShown to inhibit protein synthesis through ADP-ribosylation of elongation factor 2. Cytopathic for a number of cell lines and exhibits toxicity in animals. Has enzymatic activity identical to that of diphtheria toxin; however, it has distinct target-cell specificity and is immunologically unrelated.
          FormLyophilized
          FormulationSolid lyophilized from 150 mM NaCl, 10 mM sodium phosphate buffer, pH 7.5.
          CAS number91262-95-2
          RTECSLF2991000
          PuritySingle band by SDS-PAGE; single precipitin band by immunodiffusion
          SolubilityH₂O
          Storage +2°C to +8°C
          Do Not Freeze Yes
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.
          Toxicity Highly Toxic
          ReferencesPrentice, G.A., and Merrill, A.R. 1999. Anal. Biochem. 272, 216.