A part of MilliporeSigma

324875 | Eicosapentaenoic Acid - CAS 10417-94-4 - Calbiochem

324875
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₀H₃₀O₂ 10417-94-4

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      324875-25MG
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service

          Glass bottle 25 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          Description
          OverviewCell permeable. Shown to have a beneficial effect in cardiovascular diseases and inflammation. Causes elevation of intracellular free Ca2+. Inhibits 5-lipoxygenase and reduces thromboxane A2 production and blood viscosity. Reported to induce apoptosis in pancreatic cancer cell lines and to inhibit liver metastasis.
          Catalogue Number324875
          Brand Family Calbiochem®
          SynonymsEPA, 5,8,11,14,17-Eicosapentaenoic Acid, C20:5 ω-3
          References
          ReferencesIwamoto, S., et al. 1998. Nutr. Cancer 31, 143.
          Lai, P.B., et al. 1996. Br. J. Cancer 74, 1375.
          Marotta, F., et al. 1995. Digestion 56, 46. Kurihara, T., et al. 1994. Clin. Ther. 16, 830.
          Okuda, Y., et al. 1994. Biochem. Med. Metab. Biol. 51, 166.
          James, M.J., et al. 1993. J. Exp. Med. 178, 2261.
          chamcock, J.S., et al. 1992. Mol. Cell. Biochem. 116, 19.
          Stenson, W.F., et al. 1992. Ann. Intern. Med. 116, 609.
          Product Information
          CAS number10417-94-4
          ATP CompetitiveN
          FormClear liquid
          Hill FormulaC₂₀H₃₀O₂
          Chemical formulaC₂₀H₃₀O₂
          ReversibleN
          Structure formula Image
          Applications
          Biological Information
          Primary Target5-lipoxygenase
          Purity≥99% by GC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSJX3820000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          324875

          References

          Reference overview
          Iwamoto, S., et al. 1998. Nutr. Cancer 31, 143.
          Lai, P.B., et al. 1996. Br. J. Cancer 74, 1375.
          Marotta, F., et al. 1995. Digestion 56, 46. Kurihara, T., et al. 1994. Clin. Ther. 16, 830.
          Okuda, Y., et al. 1994. Biochem. Med. Metab. Biol. 51, 166.
          James, M.J., et al. 1993. J. Exp. Med. 178, 2261.
          chamcock, J.S., et al. 1992. Mol. Cell. Biochem. 116, 19.
          Stenson, W.F., et al. 1992. Ann. Intern. Med. 116, 609.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision02-May-2008 RFH
          SynonymsEPA, 5,8,11,14,17-Eicosapentaenoic Acid, C20:5 ω-3
          DescriptionFatty acid isolated from microscopic algae. Serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid by the extra double bond between C17 and C18. Has a beneficial effect in cardiovascular diseases and inflammation. Also acts as an antihyperlipoproteinenic agent. Causes elevations of intracellular free Ca2+. Inhibits 5-lipoxygenase and reduces thromboxane A2 production and blood viscosity.
          FormClear liquid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number10417-94-4
          RTECSJX3820000
          Chemical formulaC₂₀H₃₀O₂
          Structure formula
          Purity≥99% by GC
          SolubilityMethanol (1 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 3531
          ReferencesIwamoto, S., et al. 1998. Nutr. Cancer 31, 143.
          Lai, P.B., et al. 1996. Br. J. Cancer 74, 1375.
          Marotta, F., et al. 1995. Digestion 56, 46. Kurihara, T., et al. 1994. Clin. Ther. 16, 830.
          Okuda, Y., et al. 1994. Biochem. Med. Metab. Biol. 51, 166.
          James, M.J., et al. 1993. J. Exp. Med. 178, 2261.
          chamcock, J.S., et al. 1992. Mol. Cell. Biochem. 116, 19.
          Stenson, W.F., et al. 1992. Ann. Intern. Med. 116, 609.