513100 DL-threo-PDMP, Hydrochloride - CAS 80938-69-8 - Calbiochem

513100
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₃H₃₈N₂O₃ · HCl 80938-69-8

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      513100-50MG
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          Plastic ampoule 50 mg
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          Description
          OverviewPDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme. Blocks the outgrowth of neurites and inhibits glycolipid synthesis in cultured NIH/3T3 cells.
          Catalogue Number513100
          Brand Family Calbiochem®
          Synonyms1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, HCl
          References
          ReferencesRani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
          Rosenwald, A.G. 1992. Biochemistry 31, 3581.
          Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res. 28, 565.
          Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids 26, 265.
          Product Information
          CAS number80938-69-8
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₂₃H₃₈N₂O₃ · HCl
          Chemical formulaC₂₃H₃₈N₂O₃ · HCl
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Targetglycolipid synthesis in cultured NIH/3T3 cells
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          513100

          References

          Reference overview
          Rani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
          Rosenwald, A.G. 1992. Biochemistry 31, 3581.
          Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res. 28, 565.
          Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids 26, 265.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision19-August-2008 RFH
          Synonyms1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, HCl
          DescriptionPDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and is a potent and competitive inhibitor of this enzyme. Blocks the outgrowth of neurites and inhibits glycolipid synthesis in cultured 3T3 cells.
          FormWhite solid
          CAS number80938-69-8
          Chemical formulaC₂₃H₃₈N₂O₃ · HCl
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityDMSO, methanol, or ethanol
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
          Toxicity Irritant
          ReferencesRani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
          Rosenwald, A.G. 1992. Biochemistry 31, 3581.
          Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res. 28, 565.
          Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids 26, 265.