233153 Cleland’s Reagent, ULTROL® Grade - CAS 3483-12-3 - Calbiochem

233153
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service
      View Pricing & Availability
      Click To Print This Page

      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₄H₁₀O₂S₂ 3483-12-3

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      233153-10GM
      Retrieving availability...
      Limited AvailabilityLimited Availability
      Stocked 
      Discontinued
      Limited Quantities Available
      Available
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Plastic ampoule 10 gm
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity needs to be mulitiple of
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          233153-1GM
          Retrieving availability...
          Limited AvailabilityLimited Availability
          Stocked 
          Discontinued
          Limited Quantities Available
          Available
            Remaining : Will advise
              Remaining : Will advise
              Will advise
              Contact Customer Service
              Contact Customer Service

              Plastic ampoule 1 gm
              Retrieving price...
              Price could not be retrieved
              Minimum Quantity needs to be mulitiple of
              Upon Order Completion More Information
              You Saved ()
               
              Request Pricing
              233153-5GM
              Retrieving availability...
              Limited AvailabilityLimited Availability
              Stocked 
              Discontinued
              Limited Quantities Available
              Available
                Remaining : Will advise
                  Remaining : Will advise
                  Will advise
                  Contact Customer Service
                  Contact Customer Service

                  Plastic ampoule 5 gm
                  Retrieving price...
                  Price could not be retrieved
                  Minimum Quantity needs to be mulitiple of
                  Upon Order Completion More Information
                  You Saved ()
                   
                  Request Pricing
                  Description
                  OverviewA protective agent for SH groups.
                  Absorbance: (100 mM, 280 nm):≤0.1. Oxidized dithiothreitol:≤0.5%.
                  Catalogue Number233153
                  Brand Family Calbiochem®
                  SynonymsDithiothreitol, DTT
                  References
                  ReferencesChau, M-H., and Nelson, J.W. 1991. FEBS Lett. 291, 296.
                  Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
                  Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
                  Zhang, R., and Snyder, G.H. 1988. Biochemistry 27, 3785.
                  Shaked, Z., et al. 1980. Biochemistry 19, 4156.
                  Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
                  Cleland, W.W. 1964. Biochemistry 3, 480.
                  Product Information
                  CAS number3483-12-3
                  FormWhite solid
                  Hill FormulaC₄H₁₀O₂S₂
                  Chemical formulaC₄H₁₀O₂S₂
                  Applications
                  Biological Information
                  Purity≥99% by titration
                  Physicochemical Information
                  ContaminantsHeavy metals: <1 ppm
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  RTECSEK1610000
                  Safety Information
                  R PhraseR: 22-36/38

                  Harmful if swallowed.
                  Irritating to eyes and skin.
                  S PhraseS: 26-36

                  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
                  Wear suitable protective clothing.
                  Product Usage Statements
                  Storage and Shipping Information
                  Ship Code Ambient Temperature Only
                  Toxicity Harmful
                  Storage +2°C to +8°C
                  Do not freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Avoid contact with metals. Stock solutions are stable for up to 3 months at -20°C.
                  Packaging Information
                  Packaged under inert gas Packaged under inert gas
                  Transport Information
                  Supplemental Information
                  Specifications

                  Documentation

                  SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Certificates of Analysis

                  TitleLot Number
                  233153

                  References

                  Reference overview
                  Chau, M-H., and Nelson, J.W. 1991. FEBS Lett. 291, 296.
                  Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
                  Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
                  Zhang, R., and Snyder, G.H. 1988. Biochemistry 27, 3785.
                  Shaked, Z., et al. 1980. Biochemistry 19, 4156.
                  Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
                  Cleland, W.W. 1964. Biochemistry 3, 480.

                  Brochure

                  Title
                  Cleland's Reagent (Dithiothreitol) Technical Bulletin
                  Data Sheet

                  Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                  Revision27-August-2018 JSW
                  SynonymsDithiothreitol, DTT
                  DescriptionDTT is a water-soluble protective reagent for sulfhydryl groups. It maintains monothiols in the reduced state and reduces disulfides quantitatively. Most widely used for the study of disulfide exchange reactions of protein disulfides. DTT readily permeates cell membranes, protecting protein sulfhydryls and restoring enzyme activity lost by the oxidation of sulfhydryl groups in vitro. As a reducing agent, it cyclizes as it reduces disulfides to thiols, so the reaction is "driven" to completion without using large excesses of reductant. If free thiols are to be assayed later, excess reductant must be removed by dialysis or some other appropriate method. Alternatively, an immobilized form of DTT (REDUCTACRYL™ Reagent, Cat. No. 233157) can be used. Absorbance: (100 mM, 280 nm):≤0.05. Oxidized dithiothreitol:≤0.5%.
                  FormWhite solid
                  Intert gas (Yes/No) Packaged under inert gas
                  CAS number3483-12-3
                  RTECSEK1610000
                  Chemical formulaC₄H₁₀O₂S₂
                  Purity≥99% by titration
                  ContaminantsHeavy metals: <1 ppm
                  SolubilityEthanol or H₂O (200 mM)
                  Storage +2°C to +8°C
                  Do Not Freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Avoid contact with metals. Stock solutions are stable for up to 3 months at -20°C.
                  Toxicity Harmful
                  Merck USA index14, 3376
                  ReferencesChau, M-H., and Nelson, J.W. 1991. FEBS Lett. 291, 296.
                  Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125.
                  Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199.
                  Zhang, R., and Snyder, G.H. 1988. Biochemistry 27, 3785.
                  Shaked, Z., et al. 1980. Biochemistry 19, 4156.
                  Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716.
                  Cleland, W.W. 1964. Biochemistry 3, 480.