100241 Citric acid

100241
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      Overview

      Replacement Information

      Key Specifications Table

      CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
      77-92-9 201-069-1 C₆H₈O₇ (HOOCCH₂)₂C(OH)COOH 192.12 g/mol Ph Eur,BP,JP,USP,E 330,FCC

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      Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
      1002415000
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          Plastic bottle 5 kg
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          1.00241.9029
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              Double PE Sack 25 kg
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              Description
              Catalogue Number100241
              Synonyms2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
              DescriptionCitric acid
              References
              Product Information
              CAS number77-92-9
              EC number201-069-1
              GradePh Eur,BP,JP,USP,E 330,FCC
              Hill FormulaC₆H₈O₇
              Chemical formula(HOOCCH₂)₂C(OH)COOH
              Molar Mass192.12 g/mol
              HS Code2918 14 00
              Structure formula ImageStructure formula Image
              Applications
              Biological Information
              Physicochemical Information
              Boiling point200 °C (1013 hPa) (decomposition)
              Density1.665 g/cm3 (18 °C)
              Melting Point153 °C (decomposition)
              pH value1.7 (100 g/l, H₂O, 20 °C)
              Vapor pressure<0.1 hPa (20 °C)
              Bulk density560 kg/m3
              Solubility1330 g/l
              Dimensions
              Materials Information
              Toxicological Information
              LD 50 oralLD50 Rat 3000 mg/kg
              Safety Information according to GHS
              Hazard Pictogram(s) Hazard Pictogram(s)
              Hazard Statement(s)H319: Causes serious eye irritation.
              Precautionary Statement(s)P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
              Signal WordWarning
              RTECSGE7350000
              Storage class10 - 13 Other liquids and solids
              WGKWGK 1 slightly hazardous to water
              Safety Information
              Hazard Symbols Hazard SymbolsIrritant
              Categories of dangerirritant
              R PhraseR 36
              Irritating to eyes.
              S PhraseS 26
              In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
              Product Usage Statements
              Storage and Shipping Information
              StorageStorage temperature: no restrictions.
              Packaging Information
              Transport Information
              Declaration (railroad and road) ADR, RIDKein Gefahrgut
              Declaration (transport by air) IATA-DGRNo Dangerous Good
              Declaration (transport by sea) IMDG-CodeNo Dangerous Good
              Supplemental Information
              Specifications
              Assay (alkalimetric, calculated on anhydrous substance)99.5 - 100.5 %
              Identity (IR-spectrum)passes test
              Appearancewhite to almost white, fine powder
              Appearance of solution (200 g/l; water)clear (≤ 3 NTU) and not more intense in color than reference solution Y₇, BY₇ or GY₇
              Sulfate (SO₄)≤ 50 ppm
              Heavy metals (as Pb)≤ 5 ppm
              Al (Aluminium)≤ 0.2 ppm
              As (Arsenic)≤ 1 ppm
              Hg (Mercury)≤ 1 ppm
              Pb (Lead)≤ 0.5 ppm
              Oxalates (as C₂H₂O₄)≤ 100 ppm
              Residual solvents (ICH (Q3C))excluded by manufacturing process
              Readily carbonisable substancepasses test
              Sulfated ash (600 °C)≤ 0.05 %
              Water (according to Karl Fischer)≤ 0.5 %
              Bacterial endotoxins< 0.5
              Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
              Corresponds to Ph. Eur., BP, JP, USP, E 330, FCC
              Conforms to the purity criteria on food additives according to the current European Commission Regulation.

              Documentation

              Material Qualification Dossier

              Title

              Quality Management Dossier

              Title

              Operational Excellence Dossier

              Title

              Citric acid SDS

              Title

              Safety Data Sheet (SDS) 

              Citric acid Certificates of Analysis

              Product Number PackagingSpecificationLot Number
              1002415000 Plastic bottlePDF Specification Document
              1.00241.9029 Double PE SackPDF Specification Document

              Certificates

              Title

              Brochure

              Title
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              MultiPharmTM Minerals for Solid Dosage Forms

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              Categories

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              Small Molecule Pharmaceuticals > Formulation > Solid Dosage Form > pH Adjustment
              Small Molecule Pharmaceuticals > Formulation > Solid Dosage Form > Taste Modifiers
              Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > Taste Modifiers
              Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > Taste Modifiers
              Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers