220551 | Chloramphenicol - CAS 56-75-7 - Calbiochem

220551
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₁₁H₁₂Cl₂N₂O₅ 56-75-7

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      220551-100GM
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          Glass bottle 100 gm
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          220551-25GM
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              Plastic ampoule 25 gm
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              220551-500GM
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                  Glass bottle 500 gm
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                  Description
                  OverviewSynthetic bacteriostatic antibiotic that inhibits the translation of RNA by blocking the peptidyltransferase reaction on ribosomes.
                  Catalogue Number220551
                  Brand Family Calbiochem®
                  References
                  ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
                  Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
                  Saltarelli, M.J., et al. 1993. Virol. 197, 35.
                  Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
                  Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.
                  Product Information
                  CAS number56-75-7
                  FormGrayish to off-white crystalline powder
                  Hill FormulaC₁₁H₁₂Cl₂N₂O₅
                  Chemical formulaC₁₁H₁₂Cl₂N₂O₅
                  Structure formula ImageStructure formula Image
                  Applications
                  Biological Information
                  Biological activityPotency: ≥970 µg/mg
                  Primary Targettrasnslation of RNA
                  Purity≥97% by Assay
                  Physicochemical Information
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  RTECSAB6825000
                  Safety Information
                  Product Usage Statements
                  Storage and Shipping Information
                  Ship Code Ambient Temperature Only
                  Storage +15°C to +30°C
                  Do not freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
                  Packaging Information
                  Transport Information
                  Supplemental Information
                  Specifications

                  Documentation

                  SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Certificates of Analysis

                  TitleLot Number
                  220551

                  References

                  Reference overview
                  Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
                  Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
                  Saltarelli, M.J., et al. 1993. Virol. 197, 35.
                  Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
                  Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.

                  Brochure

                  Title
                  Antibiotics Profiler
                  Bulk Product Guide
                  Drugs for Selection of Genetic Markers Technical Bulletin
                  Overnight Express Autoinduction Systems

                  Technical Info

                  Title
                  EMD Millipore Regulated Product Information
                  Data Sheet

                  Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                  Revision07-January-2014 JSW
                  DescriptionSynthetic bacteriostatic antibiotic that inhibits the translation of RNA to protein by binding to the 50S ribosomal subunit, blocking the peptidyl transferase reaction. Chloramphenicol resistance is encoded by the resistance gene cat, whose product, chloramphenicol acetyltransferase, inactivates the antibiotic via acetylation. Typically used at 30-50 µg/ml for selection of chloramphenicol-resistant Escherichia coli.
                  FormGrayish to off-white crystalline powder
                  CAS number56-75-7
                  RTECSAB6825000
                  Chemical formulaC₁₁H₁₂Cl₂N₂O₅
                  Structure formulaStructure formula
                  Purity≥97% by Assay
                  Biological activityPotency: ≥970 µg/mg
                  SolubilityEthanol, Methanol (35 mg/ml), or H₂O (2.5 mg/ml)
                  Storage +15°C to +30°C
                  Do Not Freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
                  Merck USA index14 2077
                  ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
                  Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
                  Saltarelli, M.J., et al. 1993. Virol. 197, 35.
                  Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
                  Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.

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                  Categories

                  Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Protein Synthesis Inhibitors
                  Life Science Research > Inhibitors and Biochemicals > Biochemicals > Antibiotics > Antimicrobial Agents
                  Life Science Research > Cell Culture and Systems > Antibiotics & Selection Agents