208690 | Calmodulin, Bovine Brain

208690
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      Overview

      Replacement Information

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      208690-1MG
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          Plastic ampoule 1 mg
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          208690-5MG
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              Glass bottle 5 mg
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              Description
              OverviewA ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Calmodulin purified from bovine brain.
              Note: 1 KU = 1000 units.
              Note: this product cannot be used for animal treatment, in vivo research, or any contact procedure with livestock.
              Catalogue Number208690
              Brand Family Calbiochem®
              SynonymsCaM, Ca2+/Calmodulin
              References
              ReferencesCarl, A., et al. 1990. J. Physiol. 429, 205.
              Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res. 10, 417.
              Cheung, W.T. 1979. Science 207, 19.
              Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
              Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg. 15, 47.
              Watterson, A., et al. 1976. J. Biol. Chem. 251, 4501.
              Product Information
              CAS number73298-54-1
              Unit of DefinitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
              FormLyophilized
              FormulationLyophilized from 150 mM NaCl, 50 mM Tris-HCl, 2 mM EDTA, pH 7.6.
              Applications
              Biological Information
              Purity≥95% by SDS-PAGE
              Specific Activity≥12,500 units/mg protein
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              208690

              References

              Reference overview
              Carl, A., et al. 1990. J. Physiol. 429, 205.
              Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res. 10, 417.
              Cheung, W.T. 1979. Science 207, 19.
              Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
              Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg. 15, 47.
              Watterson, A., et al. 1976. J. Biol. Chem. 251, 4501.

              Brochure

              Title
              Calcium Metabolism and Related Products Brochure
              Calmodulin and Related Products Technical Bulletin
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision10-February-2010 JSW
              SynonymsCaM, Ca2+/Calmodulin
              DescriptionA ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate. Calmodulin purified from bovine brain.

              Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
              FormLyophilized
              FormulationLyophilized from 150 mM NaCl, 50 mM Tris-HCl, 2 mM EDTA, pH 7.6.
              CAS number73298-54-1
              Purity≥95% by SDS-PAGE
              Specific activity≥12,500 units/mg protein
              Unit definitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
              SolubilityAqueous buffers or H₂O
              Storage -20°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
              Toxicity Standard Handling
              Merck USA index14, 1719
              ReferencesCarl, A., et al. 1990. J. Physiol. 429, 205.
              Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res. 10, 417.
              Cheung, W.T. 1979. Science 207, 19.
              Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
              Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg. 15, 47.
              Watterson, A., et al. 1976. J. Biol. Chem. 251, 4501.