208922 | CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem

208922
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical FormulaCAS #
      C₂₁H₃₇N₇O₃ 140651-18-9

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      208922-5MG
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          Glass bottle 5 mg
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          Description
          OverviewA cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC50 <10 µM) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 µM) and GLUT4 membrane translocation (IC50 = 100 µM) in 3T3-L1 adipocytes.
          Catalogue Number208922
          Brand Family Calbiochem®
          Synonyms2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59
          References
          ReferencesKonstantopoulos, N., et al. 2007. Endocrinology, 148, 374.
          Product Information
          CAS number140651-18-9
          FormYellow semi-solid
          Hill FormulaC₂₁H₃₇N₇O₃
          Chemical formulaC₂₁H₃₇N₇O₃
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Purity≥95% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          208922

          References

          Reference overview
          Konstantopoulos, N., et al. 2007. Endocrinology, 148, 374.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision19-February-2014 JSW
          Synonyms2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59
          DescriptionA cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC50 <10 µM) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 µM) and GLUT4 membrane translocation (IC50 = 100 µM) in 3T3-L1 adipocytes.
          FormYellow semi-solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number140651-18-9
          Chemical formulaC₂₁H₃₇N₇O₃
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (10 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesKonstantopoulos, N., et al. 2007. Endocrinology, 148, 374.