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05-23-3831 | BQ-123, Sodium Salt - CAS - Calbiochem

05-23-3831
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₃₁H₄₁N₆O₇ · Na

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      05-23-3831-1MG
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          Glass bottle 1 mg
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          05-23-3831-5MG
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              Glass bottle 5 mg
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              Description
              OverviewA highly potent, selective, and competitive ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus Ki = 2.5 μM for ETB).
              Catalogue Number05-23-3831
              Brand Family Calbiochem®
              References
              ReferencesNambi, P., et al. 1996. J. Pharmacol. Exp. Ther. 277, 1567.
              Bax, W.A., and Saxena, P.R. 1994. Trends Pharmacol. Sci. 15, 379.
              Ihara, M., et al. 1991. Biochem. Biophys. Res. Commun. 178, 132.
              Product Information
              ATP CompetitiveN
              FormWhite solid
              FormulationSupplied as a sodium salt. Sold on the basis of peptide content.
              Hill FormulaC₃₁H₄₁N₆O₇ · Na
              Chemical formulaC₃₁H₄₁N₆O₇ · Na
              Hygroscopic Hygroscopic
              ReversibleN
              Sold on the basis of peptide contentY
              Applications
              Biological Information
              Primary TargetETA (endothelin) receptor antagonist
              Primary Target K<sub>i</sub>40 nM for ETA versus 2.5 µM for ETB
              Purity≥95% by HPLC
              Physicochemical Information
              Cell permeableN
              Peptide ContentY
              Peptide SequenceCyclo(D-Asp-Pro-D-Val-Leu-D-Trp, Na)
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage -20°C
              Hygroscopic Hygroscopic
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              SDS

              Title

              Safety Data Sheet (SDS) 

              Certificates of Analysis

              TitleLot Number
              05-23-3831

              References

              Reference overview
              Nambi, P., et al. 1996. J. Pharmacol. Exp. Ther. 277, 1567.
              Bax, W.A., and Saxena, P.R. 1994. Trends Pharmacol. Sci. 15, 379.
              Ihara, M., et al. 1991. Biochem. Biophys. Res. Commun. 178, 132.
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision31-May-2011 JSW
              DescriptionA highly potent and selective ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus 2.5 µM for ETB).
              FormWhite solid
              FormulationSupplied as a sodium salt. Sold on the basis of peptide content.
              Chemical formulaC₃₁H₄₁N₆O₇ · Na
              Peptide SequenceCyclo(D-Asp-Pro-D-Val-Leu-D-Trp, Na)
              Purity≥95% by HPLC
              SolubilityH₂O (1 mg/ml)
              Storage -20°C
              Hygroscopic
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
              Toxicity Standard Handling
              ReferencesNambi, P., et al. 1996. J. Pharmacol. Exp. Ther. 277, 1567.
              Bax, W.A., and Saxena, P.R. 1994. Trends Pharmacol. Sci. 15, 379.
              Ihara, M., et al. 1991. Biochem. Biophys. Res. Commun. 178, 132.