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S7200 | ApopTag® Peroxidase In Situ Oligo Ligation (ISOL) Kit

S7200
40 assays  
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      Overview

      Replacement Information

      Key Specifications Table

      Key ApplicationsDetection Methods
      IHC, IH(P) Chromogenic
      Description
      Catalogue NumberS7200
      Brand Family Chemicon®
      Trade Name
      • ApopTag
      • Chemicon
      DescriptionApopTag® Peroxidase In Situ Oligo Ligation (ISOL) Kit
      OverviewThe ApopTag® Peroxidase In Situ Oligo Ligation Kit specifically detects apoptosis by staining only cells that contain double-stranded breaks that are blunt-ended or have a one base 3' overhang (cells containing nicked, gapped, 3'-recessed, 3'-overhanging ends longer than one base and single-stranded ends are not detected). The high analytic specificity of the ApopTag® ISOL Kit minimizes background due to non-specific labeling of DNA. The specificity can be exploited to more readily identify apoptosis in systems presenting cells with both apoptosis and DNA damage or apoptosis and necrosis. Results are visualized using brightfield microscopy.
      References
      Product Information
      Detection methodChromogenic
      Applications
      ApplicationThe ApopTag Peroxidase In Situ Oligo Ligation Kit specifically detects apoptosis by staining only cells that contain double-stranded breaks that are blunt-ended or have a one base 3' overhang.
      Key Applications
      • Immunohistochemistry
      • Immunohistochemistry (Paraffin)
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size40 assays
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overviewPub Med ID
      Interleukin-10 delivery via mesenchymal stem cells: a novel gene therapy approach to prevent lung ischemia-reperfusion injury.
      Manning E, Pham S, Li S, Vazquez-Padron RI, Mathew J, Ruiz P, Salgar SK
      Hum Gene Ther 21 713-27. 2010

      Show Abstract
      20102275 20102275
      Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression.
      Rosa Quiles-Perez,José Antonio Muñoz-Gámez,Angeles Ruiz-Extremera,Francisco O'Valle,Laura Sanjuán-Nuñez,Ana Belén Martín-Alvarez,David Martín-Oliva,Trinidad Caballero,Paloma Muñoz de Rueda,Josefa León,Raúl Gonzalez,Jordi Muntané,Francisco Javier Oliver,Javier Salmerón
      Hepatology (Baltimore, Md.) 51 2010

      Show Abstract
      20034026 20034026
      Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats
      Fong, Louise Y Y, et al
      J Natl Cancer Inst, 97:40-50 (2005) 2005

      15632379 15632379

      Brochure

      Title
      Advancing cancer research: From hallmarks & biomarkers to tumor microenvironment progression
      Comprehensive solutions for studying cell health - Life, death, and everything in between.

      Technical Info

      Title
      A Comparative Analysis of Human Embryonic Stem Cells Cultured in a Variety of Media Conditions

      User Guides

      Title
      ApopTag® Peroxidase In Situ Oligo Ligation (ISOL) Apoptosis Detection Kit

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      Product Families

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      Categories

      Life Science Research > Cell Analysis > Cell-based Assays > Apoptosis / Cell Death Assays