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05-1951-AF488 | Anti-trimethyl Histone H3 (Lys27) Antibody, clone 18E9.1, Alexa Fluor® 488 Conjugate

05-1951-AF488
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M ICC M AlexaFluor®488 Monoclonal Antibody
      Description
      Catalogue Number05-1951-AF488
      DescriptionAnti-trimethyl Histone H3 (Lys27) Antibody, clone 18E9.1, Alexa Fluor® 488 Conjugate
      Alternate Names
      • Histone H3.3
      • H3F3A
      • H3.3A
      • H3F3
      Background InformationHistone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
      References
      Product Information
      FormatAlexaFluor®488
      PresentationPurified mouse conjugate in buffer containing PBS, 15 mg/ml BSA, and 0.1% Sodium Azide.
      Applications
      ApplicationThis Anti-trimethyl Histone H3 (Lys27) Antibody, clone 18E9.1, Alexa Fluor® 488 Conjugate is validated for use in ICC for the detection of trimethyl Histone H3 (Lys27).
      Key Applications
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: A 1:100 dilution from a representative lot detected trimethyl Histone H3 (Lys27) in NIH/3T3 cells.
      Biological Information
      ImmunogenLinear peptide corresponding to trimethyl Histone H3 (Lys27).
      Clone18E9.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • H3F3B
      • H3.3B
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight17 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry Analysis in HepG2 cells

      Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected trimethyl Histone H3 (Lys27) in HepG2 cells.

      Alexa Fluor® is a registered trademark of Life Technologies®.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications