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05-590 | Anti-phospho-STAT6 (Tyr641) Antibody, clone 16E12

100 µg  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R WB M Purified Monoclonal Antibody
      Catalogue Number05-590
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-phospho-STAT6 (Tyr641) Antibody, clone 16E12
      Product Information
      Presentation100µg of lyophilized thiophilic and size exclusion chromatography purified mouse IgG1 from 1mL 2x PBS / 0.09 % Na-azide / PEG and Sucrose. Reconstitute with 100 µL H2O (15 min, RT) for a final concentration of 1 mg/mL. Store at -20°C.
      ApplicationDetect phospho-STAT6 (Tyr641) also known as signal transducer & activator of transcription 6 with Anti-phospho-STAT6 (Tyr641) Antibody, clone 16E12 (mouse monoclonal antibody), that has been demonstrated to work in WB.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenPeptide corresponding to residues of human STAT6 (Tyr641); recognizes STAT6 phosphorylated on Tyrosine 641.
      Cloneclone 16E12
      Specificityphosphorylated STAT6
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.
      Gene Symbol
      • STAT6
      • STAT6C
      • D12S1644
      • STAT6B
      • IL-4-STAT
      • Phosphorylation
      Purification MethodThiophilic adsoption and size exclusion chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P42226 # Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.
      SIZE: 847 amino acids; 94135 Da
      SUBUNIT: Forms a homodimer or a heterodimer with a related family member (By similarity). Interacts with NCOA1 via its C-terminal LXXLL motif.
      SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
      PTM: Tyrosine phosphorylated following stimulation by IL-4 and IL- 3 (By similarity).
      SIMILARITY: SwissProt: P42226 ## Belongs to the transcription factor STAT family. & Contains 1 SH2 domain.
      Molecular Weight100kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on RIPA lysates from IL4-stimulated HepG2 cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-phospho-STAT6 (Tyr641) - 20253 20253
      Anti-phospho-STAT6 (Tyr641) - 25346 25346
      Anti-phospho-STAT6 (Y641), clone 16E12 (mouse monoclonal IgG1) - 2433264 2433264
      Anti-phospho-STAT6 (Y641), clone 16E12 (mouse monoclonal IgG1) - 1951497 1951497
      Anti-phospho-STAT6 (Y641), clone 16E12 (mouse monoclonal IgG1) - 2110471 2110471
      Anti-phospho-STAT6 (Y641), clone 16E12 (mouse monoclonal IgG1) - 2210329 2210329
      Anti-phospho-STAT6 (Y641), clone 16E12 (mouse monoclonal IgG1) - 2274021 2274021
      Anti-phospho-STAT6 (Y641), clone 16E12 (mouse monoclonal IgG1) - 2326975 2326975
      Anti-phospho-STAT6 (Y641), clone 16E12 - 2031317 2031317
      Anti-phospho-STAT6 (Y641), clone 16E12 - 2033626 2033626
      Anti-phospho-STAT6 (Y641), clone 16E12 - 2068411 2068411
      Anti-phospho-STAT6 (Y641), clone 16E12 - DAM1535699 DAM1535699
      Anti-phospho-STAT6 (Y641), clone 16E12 - DAM1655251 DAM1655251
      Anti-phospho-STAT6 (Y641), clone 16E12 - DAM1676167 DAM1676167
      Anti-phospho-STAT6 (Y641), clone 16E12 - DAM1724024 DAM1724024
      Anti-phospho-STAT6 (Y641), clone 16E12 - DAM1751927 DAM1751927
      Anti-phospho-STAT6 (Y641), clone 16E12 - DAM1751927 DAM1751927
      Anti-phospho-STAT6 (Y641), clone 16E12 - DAM1807791 DAM1807791
      Anti-phospho-STAT6 (Y641), clone 16E12 - NG1915695 NG1915695
      Anti-phospho-STAT6 (Y641), clone 16E12 - NG1946490 NG1946490


      Pathways and Biomarkers of JAK/STAT Signaling

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      Life Science Research > Antibodies and Assays > Primary Antibodies