09-836 Anti-phospho-Histone H1.B (Ser27) Antibody

09-836
100 ug  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, Mplex Rb Purified Polyclonal Antibody
      Description
      Catalogue Number09-836
      DescriptionAnti-phospho-Histone H1.B (Ser27) Antibody
      Background InformationHistones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into 30nm chromatin fibers and higher order structures.
      References
      Product Information
      FormatPurified
      Control
      • Untreated and colcemid-treated HeLa acid extract.
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide.
      Applications
      ApplicationAnti-phospho-Histone H1.B (Ser27) Antibody is a high quality Rabbit Polyclonal Antibody for the detection of phospho-Histone H1.B (Ser27) & has been validated in WB, Mplex.
      Key Applications
      • Western Blotting
      • Multiplexing
      Biological Information
      ImmunogenKLH-conjugated synthetic linear peptide corresponding to the region at and around phosphorylated serine 27 of histone H1.B.
      EpitopePhosphorylated H1.B (Ser27)
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes phosphorylated serine 27 at and around the N-terminal region of histone H1.B.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Modifications
      • Phosphorylation
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight35 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by western blot on untreated and colcemid-treated HeLa acid extract.

      Western Blotting Analysis: 0.1 µg/mL of this antibody detected phospho-Histone H1.B (Ser27) in untreated and colcemid-treated HeLa acid extract.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8ºC from date of receipt.
      Packaging Information
      Material Size100 ug
      Transport Information
      Supplemental Information
      Specifications

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      Product Families

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies