A part of MilliporeSigma

AB15466 | Anti-Zic3 Antibody

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB Rb Affinity Purified Polyclonal Antibody
      Catalogue NumberAB15466
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Zic3 Antibody
      Alternate Names
      • Zinc finger protein Zic3
      Product Information
      FormatAffinity Purified
      PresentationLiquid in PBS with 0.1% sodium azide.
      ApplicationThis Anti-Zic3 Antibody is validated for use in WB for the detection of Zic3.
      Key Applications
      • Western Blotting
      Application NotesWestern blot: 1.0-5.0 μg/mL on human brain lysate.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide
      SpecificityZic3 (Zinc finger protein). By Western blot the antibody recognizes a band at ~56 kDa in human brain lysate.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.
      Gene Symbol
      • ZIC3
      • HTX1
      • ZNF203
      • HTX
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: O60481 # Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation.
      SIZE: 467 amino acids; 50569 Da
      DISEASE: SwissProt: O60481 # Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1) [MIM:306955]. HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs, including asplenia or polysplenia, symmetric liver, intestinal malrotation, and abnormal lung lobation.
      SIMILARITY: SwissProt: O60481 ## Belongs to the GLI C2H2-type zinc-finger protein family. & Contains 4 C2H2-type zinc fingers.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information