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MAB5470 | Anti-Vasoactive Intestinal Peptide Receptor 2 Antibody

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R IHC, WB M Purified Monoclonal Antibody
      Catalogue NumberMAB5470
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Vasoactive Intestinal Peptide Receptor 2 Antibody
      Alternate Names
      • VIPR2
      Product Information
      PresentationPurified immunoglobulin. Liquid in PBS containing 0.08% sodium azide.
      ApplicationAnti-Vasoactive Intestinal Peptide Receptor 2 Antibody is an antibody against Vasoactive Intestinal Peptide Receptor 2 for use in IH & WB.
      Key Applications
      • Immunohistochemistry
      • Western Blotting
      Application NotesWestern blot: 1-10 μg/mL on A431 cell lysate. Reacts with the 47 kD protein. Immunhistochemistry on paraformaldehyde fixed tissue sections.

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenSynthetic peptide from human VIPR2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityReacts with Vasoactive intestinal peptide receptor 2 (VIPR2).
      Species Reactivity
      • Human
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryVasoactive intestinal peptide (VIP; MIM 192320) and pituitary adenylate cyclase activating polypeptide (PACAP; MIM 102980) are homologous peptides that function as neurotransmitters and neuroendocrine hormones. While the receptors for VIP and PACAP share homology, they differ in their substrate specificities and expression patterns. See VIPR1 (MIM 192321) and ADCYAP1R1(MIM 102981).[supplied by OMIM]
      Gene Symbol
      • VIPR2
      • VPAC2
      • FLJ16511
      • VIP-R-2
      • VPCAP2R
      • VIP2R
      • PACAP-R-3
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P41587 # This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.
      SIZE: 438 amino acids; 49479 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      SIMILARITY: SwissProt: P41587 ## Belongs to the G-protein coupled receptor 2 family.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 


      Reference overviewPub Med ID
      Corneal endothelial autocrine VIP enhances its integrity in stored human donor corneoscleral explant.
      Koh, SW; Gloria, D; Molloy, J
      Investigative ophthalmology & visual science 52 5632-40 2011

      Show Abstract
      21482640 21482640
      VIP down-regulates the inflammatory potential and promotes survival of dying (neural crest-derived) corneal endothelial cells ex vivo: necrosis to apoptosis switch and up-regulation of Bcl-2 and N-cadherin.
      Shay-Whey M Koh, Jason Cheng, Rebecca M Dodson, Chao-Yar T Ku, Cara J Abbondandolo, Shay-Whey M Koh, Jason Cheng, Rebecca M Dodson, Chao-Yar T Ku, Cara J Abbondandolo, Shay-Whey M Koh, Jason Cheng, Rebecca M Dodson, Chao-Yar T Ku, Cara J Abbondandolo, Shay-Whey M Koh, Jason Cheng, Rebecca M Dodson, Chao-Yar T Ku, Cara J Abbondandolo
      Journal of neurochemistry 109 792-806 2009

      Show Abstract Full Text Article
      19250342 19250342

      Data Sheet

      Anti-Vasoactive Intestinal Peptide Receptor 2 - Data Sheet

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      Life Science Research > Antibodies and Assays > Primary Antibodies