A part of MilliporeSigma

MABN522 | Anti-TrpC7 Antibody, clone N64A/36

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R, M WB, IHC M Purified Monoclonal Antibody
      Catalogue NumberMABN522
      DescriptionAnti-TrpC7 Antibody, clone N64A/36
      Alternate Names
      • Short transient receptor potential channel 7
      • TrpC7
      • Transient receptor protein 7
      • TRP-7
      • hTRP7
      Background InformationShort transient receptor potential channel 7 (TrpC7) is also known as Transient receptor protein 7 (TRP-7). TrpC7 is thought to create a receptor-activated non-selective calcium cation channel which is probably is controlled by a phosphatidylinositol second messenger system. TrpC7 is activated by receptor tyrosine kinases, G-protein coupled receptors, or diacylglycerol (DAG) and perhaps intracellular calcium store depletion.
      Product Information
      • Rat brain tissue lysate
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      ApplicationDetect TRPC-7 using this mouse monoclonal antibody, Anti-TrpC7 Antibody, clone N64A/36 validated for use in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 1.0 µg/mL from a representative lot detected TrpC7 in 10 µg of human brain tissue lysate.
      Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected TrpC7 in rat brain tissue.
      Biological Information
      ImmunogenLinear peptide corresponding to the C-terminus of human TrpC7.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityThis antibody recognizes the C-terminus of TrpC7
      Species Reactivity
      • Human
      • Rat
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TRPC7
      • TRP7
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~ 90 kDa observed. Uniprot describes 3 isoforms produced by alternative splicing at ~100 kDa, ~86 kDa, and ~93 kDa. Compared with isoform 1, isoform 2 is missing amino acids 260-370, and isoform 3 is missing amino acids 260-320.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected TrpC7 in 10 µg of rat brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information