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MAB1911 | Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8

100 µg  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H ELISA, WB, ICC, IHC M Purified Monoclonal Antibody
      Catalogue NumberMAB1911
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Tenascin Antibody, type III repeats 1-3, clone 9F8
      Product Information
      PresentationLiquid in 0.02 M phosphate, 0.25 M Sodium Chloride pH 7.6, with 0.1% Sodium Azide.
      ApplicationThis Anti-Tenascin Antibody, type III repeats 1-3, clone 9F8 is validated for use in ELISA, WB, IC, IH for the detection of Tenascin.
      Key Applications
      • ELISA
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesImmunohistochemistry at 2 μg/mL on tissues fixed with cold acetone

      Immunocytochemistry at 2 μg/mL on U251 cells

      Immunoblotting (Western) at 2 μg/mL to detect whole tenascin under reducing conditions

      ELISA: 2 x 10-10 M endpoint dilution

      Affinity constant Kd= 6.37 x 10-9

      Final working dilutions must be determined by end user.
      Biological Information
      ImmunogenPurified human tenascin
      Epitopetype III repeats 1-3
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      SpecificityBinds to a recombinant fragment of human tenascin containing the fibronectin type III repeats, numbers 1-3.
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Some integrin alpha M proteins contain an inserted amino acid (Q, between AA positions 499 and 500) resulting from a 3bp shift in a splice acceptor that inserts the codon CAG; receptors with or without the extra amino acid are functionally indistinguishable
      Gene Symbol
      • ITGAM
      • MO1A
      • CD11b
      • CR3A
      • MAC1A
      • CD11B
      • MGC117044
      • MAC-1
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P11215 # Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
      SIZE: 1152 amino acids; 127179 Da
      SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-M associates with beta-2.
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      TISSUE SPECIFICITY: Predominantly expressed in monocytes and granulocytes.
      DOMAIN: SwissProt: P11215 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
      SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at 2 and 8°C for up to 6 months.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-HUMAN TENASCIN -2504866 2504866
      MOUSE ANTI-HUMAN TENASCIN -2545384 2545384
      MOUSE ANTI-HUMAN TENASCIN -2575778 2575778
      MOUSE ANTI-HUMAN TENASCIN -2595355 2595355
      MOUSE ANTI-HUMAN TENASCIN -2788157 2788157
      MOUSE ANTI-HUMAN TENASCIN -2792912 2792912


      Reference overviewPub Med ID
      Identification of novel and distinct binding sites within tenascin-C for soluble and fibrillar fibronectin.
      To, WS; Midwood, KS
      The Journal of biological chemistry 286 14881-91 2011

      Show Abstract
      21324901 21324901

      Data Sheet

      Anti-Tenascin, type III repeats 1-3, clone 9F8 - Data Sheet

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      Life Science Research > Antibodies and Assays > Primary Antibodies