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ABF318 | Anti-TIRP Antibody

ABF318
100 μg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB, ICC Rb Affinity Purified Polyclonal Antibody
      Description
      Catalogue NumberABF318
      DescriptionAnti-TIRP Antibody
      Alternate Names
      • TIR domain-containing adapter molecule 2
      • TICAM-2
      • Putative NF-kappa-B-activating protein 502
      • TRIF-related adapter molecule
      • Toll-like receptor adaptor protein 3
      • Toll/interleukin-1 receptor domain-containing protein
      • MyD88-4
      Background InformationToll/interleukin-1 receptor domain-containing protein (TIRP), also known as TIR domain-containing adapter molecule 2 (TICAM2), also known as Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule (TRAM), and Toll-like receptor adaptor protein 3 (TIRAP3), is an adaptor protein containing one TIR domain, and is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) serving as an important link between the innate and adaptive immune responses. TIRP is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
      Applications
      ApplicationThis Anti-TIRP Antibody is validated for use in Western Blotting_x000D_ and Immunocytochemistry for the detection of TIRP.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis (ICC): 10 μg/mL from a representative lot detected TIRP in Raji cells.

      Biological Information
      ImmunogenTIRP antibody was raised against a peptide corresponding to 16 amino acids at the C-terminus of human TIRP.
      EpitopeC-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • TICAM2
      • TIRAP3
      • TIRP
      • TRAM
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~27 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in PC-3 cell lysate.

      Western Blotting Analysis (WB): 1 μg/mL of this antibody detected TIRP in PC-3 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies