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MABN1138 | Anti-THOC5, clone EPR6905(B), Rabbit Monoclonal Antibody

100 µL  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M WB Rb Unpurified Monoclonal Antibody
      Catalogue NumberMABN1138
      DescriptionAnti-THOC5, clone EPR6905(B), Rabbit Monoclonal Antibody
      Alternate Names
      • THO complex subunit 5 homolog
      • Functional spliceosome-associated protein 79
      • fSAP79
      • NF2/meningioma region protein pK1.3
      • Placental protein 39.2
      • PP39.2
      • hTREX90
      • THOC5
      Background InformationTHO complex subunit 5 homolog, also known as Functional spliceosome-associated protein 79 (fSAP79) or NF2/meningioma region protein pK1.3 or Placental protein 39.2 (PP39.2) or hTREX90, and encoded by the gene name THOC5, is a member of THO complex, functions in the tip associating protein (TAP)-p15 mediated nuclear export of Hsp70 mRNA. THOC5 affects granulocyte/macrophage differentiation and adipocyte differentiation, and it further supports the idea that the THO complex has a key role not only in early embryogenesis, but also in differentiation. THOC5 is localized to the nucleus and highly expressed in neutrophil/macrophage progenitor cells.
      Product Information
      PresentationRabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
      ApplicationThis Anti-THOC5 antibody is validated for use in Western Blotting for the detection of THOC5.
      Key Applications
      • Western Blotting
      Application NotesProduced in collaboration with Epitomics™
      Biological Information
      ImmunogenSynthetic peptide corresponding to human THOC5.
      ConcentrationPlease refer to lot specific datasheet.
      SpecificityEquilibrium disassociation constant (KD) is 4.40 x 10 -11 M
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • THOC5
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~79 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HEK293, HeLa, NIH/3T3, and A549 cell lysates.

      Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected THOC5 in HEK293, HeLa, NIH/3T3, and A549 cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information