574597 | Anti-Superoxide Dismutase (Cu/Zn Enzyme) Sheep pAb

574597
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityHostAntibody Type
      H, Mk, M, R Sh Polyclonal Antibody

      Pricing & Availability

      Catalog NumberAvailability Packaging Qty/Pack Price Quantity
      574597-1ML
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      Limited AvailabilityLimited Availability
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          Plastic ampoule 1 ml
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          Description
          OverviewRecognizes Cu/Zn SOD in red blood cells. Does not cross-react with Mn SOD.
          Catalogue Number574597
          Brand Family Calbiochem®
          SynonymsAnti-SOD
          References
          ReferencesPasinelli, P., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15763.
          Product Information
          FormLiquid
          FormulationIn glycine-buffered saline, pH 7.4.
          Positive controlHuman red blood cell lysate
          Preservative≤0.1% sodium azide
          Applications
          Key Applications Free-floating Sections
          Frozen Sections
          Immunoblotting (Western Blotting)
          Immunoelectrophoresis
          Paraffin Sections
          Application NotesImmunoblotting (1:1000)
          Immunoelectrophoresis (see comments)
          Frozen sections (see comments)
          Paraffin sections (see comments)
          Free-floating sections (see comments)
          Application CommentsThis antibody is monospecific as determined by immunoelectrophoresis against human red blood cell lysate and confirmed by immunodiffusion against a human red blood cell lysate and a known anti-SOD (Cu/Zn) antibody. Does not exhibit cross-reactivity with SOD (Mn) by double diffusion or with human serum. This antibody is reported to be suitable for use with free-floating, frozen, or paraffin embedded sections when used in immunohistochemistry. Variables assocated with assay conditions will dictate the proper working dilution.
          Biological Information
          Immunogenhighly purified, human erythrocyte SOD Cu/Zn.
          ImmunogenHuman
          HostSheep
          IsotypeIgG
          Species Reactivity
          • Human
          • Monkey
          • Mouse
          • Rat
          Antibody TypePolyclonal Antibody
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Avoid freeze/thaw Avoid freeze/thaw
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          574597

          References

          Reference overview
          Pasinelli, P., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15763.

          Brochure

          Title
          Nitric Oxide and Oxidative Stress Brochure

          Citations

          Title
        • Yu-Chin Lien, et al. (2006) Tumor necrosis factor receptor deficiency exacerbated Adriamycin-induced cardiomyocytes apoptosis: an insight into the Fas connection. Molecular Cancer Therapeutics 5, 261-269.
        • Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision16-August-2007 RFH
          SynonymsAnti-SOD
          ApplicationImmunoblotting (1:1000)
          Immunoelectrophoresis (see comments)
          Frozen sections (see comments)
          Paraffin sections (see comments)
          Free-floating sections (see comments)
          DescriptionSheep polyclonal antibody purified by DEAE ion-exchange chromatography. Recognizes the Cu/Zn superoxide dismutase protein.
          BackgroundSuperoxide dismutase Cu/Zn enzyme (SOD (Cu/Zn)) is a homodimeric metalloenzyme of aerobic organisms, comprised of subunits of ~16 kDa. Found in a variety of cell types, including erythrocytes, liver, and brain, it serves to protect cells against the oxidative damage of free radicals by catalyzing the conversion of superoxide anions (O2-) to molecular oxygen (O2) and hydrogen peroxide (H2O2).
          HostSheep
          Immunogen speciesHuman
          Immunogenhighly purified, human erythrocyte SOD Cu/Zn.
          IsotypeIgG
          Specieshuman, monkey, mouse, rat
          Positive controlHuman red blood cell lysate
          FormLiquid
          FormulationIn glycine-buffered saline, pH 7.4.
          Concentration Label Please refer to vial label for lot-specific concentration
          Preservative≤0.1% sodium azide
          CommentsThis antibody is monospecific as determined by immunoelectrophoresis against human red blood cell lysate and confirmed by immunodiffusion against a human red blood cell lysate and a known anti-SOD (Cu/Zn) antibody. Does not exhibit cross-reactivity with SOD (Mn) by double diffusion or with human serum. This antibody is reported to be suitable for use with free-floating, frozen, or paraffin embedded sections when used in immunohistochemistry. Variables assocated with assay conditions will dictate the proper working dilution.
          Storage -20°C
          Avoid freeze/thaw
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Standard Handling
          ReferencesPasinelli, P., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15763.
          Citation
        • Yu-Chin Lien, et al. (2006) Tumor necrosis factor receptor deficiency exacerbated Adriamycin-induced cardiomyocytes apoptosis: an insight into the Fas connection. Molecular Cancer Therapeutics 5, 261-269.