A part of MilliporeSigma

AB10537 | Anti-Sox4 Antibody

100 µL  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
Request Pricing
Limited AvailabilityLimited Availability
Limited Quantities Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers


      Contact Customer Service

      Click To Print This Page


      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M IHC Rb Serum Polyclonal Antibody
      Catalogue NumberAB10537
      DescriptionAnti-Sox4 Antibody
      Alternate Names
      • SRY (sex determining region Y)-box 4
      • ecotropic viral integration site 16
      • SRY-related HMG-box gene 4
      • SRY-box containing gene 4
      Background InformationSox4 is a protein transcription factor belonging to a family of transcription factors consisting of well over 14 members and 7 different subgroups. Members of the Sox family are characterized by DNA binding domains showing strong similarity to HMG box domains.
      Proteins belonging to the Sox family are involved in various phases of embryonic development including; neural development, hemopoiesis, lens development, chondrogenesis, and sex determination as well as cell fate. Sox4 is a part of the C subgroup of Sox proteins, and is involved in B cell and endocardial ridge development. During embryonic development, Sox4 expression has been observed in several tissues including; lung, gonads, embryonic heart, mesonephros, CNS, thymus, tooth buds, and T and pre-B cells. Sox4 has also been observed in mature tissue, especially in the pancreas, heart, lung, CHS, thymus, and gonads. Recent studies have linked overexpression of Sox4 to the development of various types of tumors and cancers, and indicating a potential for Sox4 as a therapeutic marker.
      Product Information
      • Mouse embryo pancreas tissue
      PresentationRabbit polyclonal serum containing 0.05% sodium azide.
      ApplicationUse Anti-Sox4 Antibody (Rabbit Polyclonal Antibody) validated in IHC to detect Sox4 also known as SRY (sex determining region Y)-box 4, ecotropic viral integration site 16.
      Key Applications
      • Immunohistochemistry
      Application NotesWestern Blotting: Using 1:1000 dilution of a representative lot of this antibody and lysate of human pancreas, a faint band was observed at ~48 kDa with a stronger uncharacterized band observed at ~38 kDa.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to mouse Sox4.
      SpecificityThis antibody recognizes Sox4.
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SOX4
      • EVI16
      Purification MethodUnpurified
      UniProt Number
      Molecular WeightCalculated MW ~45 kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in mouse embryo pancreas tissue.

      Immunohistochemistry Analysis: 1:300 dilution of this antibody detected Sox4 in mouse embryo pancreas tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Sox4 - 2437715 2437715
      Anti-Sox4 - 1951085 1951085
      Anti-Sox4 - 2293537 2293537
      Anti-Sox4 - NG1843437 NG1843437
      Anti-Sox4 - NRG1757203 NRG1757203
      Anti-Sox4 -2679391 2679391


      Reference overviewPub Med ID
      Cis-regulatory control of corticospinal system development and evolution.
      Shim, S; Kwan, KY; Li, M; Lefebvre, V; Sestan, N
      Nature 486 74-9 2012

      Show Abstract
      22678282 22678282