MAB352 Anti-Serotonin Antibody, clone YC5/45

MAB352
100 µL  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, Po, R, Rb, Lz, M IHC R Culture Supernatant Monoclonal Antibody
      Description
      Catalogue NumberMAB352
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Serotonin Antibody, clone YC5/45
      Alternate Names
      • 5-HT
      References
      Product Information
      FormatCulture Supernatant
      Control
      • Brain tissue
      PresentationUnPurified tissue culture supernatant containing 0.01% thimerosal as a perservative.
      Applications
      ApplicationAnti-Serotonin Antibody, clone YC5/45 is an antibody against Serotonin for use in IH.
      Key Applications
      • Immunohistochemistry
      Application NotesImmunohistochemistry at 1:100-1:200 for formaldehyde fixed tissue.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSerotonin conjugated to BSA.
      CloneYC5/45
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRat
      SpecificityRecognizes the formaldehyde conjugate of serotonin. Without paraformaldehyde treatment, it cross-reacts in liquid phase with dopamine and tryptamine in hemagglutination tests. Shows no reactivity with catecholamine-containing neurons in formaldehyde fixed preparations. MAB352 reacts with serotonin in neurons and recognizes serotonergic sites in fixed tissue sections. By cell agglutination, no cross reactivity with 5-hydroxyindolacetic acid, GABA, noradrenaline, 5-hydroxytryptophan, carnosine or melatonin.
      IsotypeIgG
      Species Reactivity
      • Human
      • Pig
      • Rat
      • Rabbit
      • Lizard
      • Mouse
      Antibody TypeMonoclonal Antibody
      Purification MethodUnpurified
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      RAT ANTI-SEROTONIN MONOCLONAL ANTIBODY - 24203692420369
      RAT ANTI-SEROTONIN MONOCLONAL ANTIBODY - 24590422459042
      RAT ANTI-SEROTONIN - 31748813174881
      RAT ANTI-SEROTONIN -25214832521483
      RAT ANTI-SEROTONIN -26183262618326
      RAT ANTI-SEROTONIN -27078392707839
      RAT ANTI-SEROTONIN -27465542746554
      RAT ANTI-SEROTONIN -27572002757200
      RAT ANTI-SEROTONIN -28171722817172
      RAT ANTI-SEROTONIN 0 -26778972677897

      References

      Reference overviewApplicationSpeciesPub Med ID
      3-D imaging and illustration of mouse intestinal neurovascular complex.
      Fu, YY; Peng, SJ; Lin, HY; Pasricha, PJ; Tang, SC
      American journal of physiology. Gastrointestinal and liver physiology  304  G1-11  2013

      Show Abstract
      Mouse23086917 23086917
      Presenilin1 regulates histamine neuron development and behavior in zebrafish, danio rerio.
      Sundvik, M; Chen, YC; Panula, P
      The Journal of neuroscience : the official journal of the Society for Neuroscience  33  1589-97  2013

      Show Abstract
      23345232 23345232
      Monoaminergic modulation of photoreception in ascidian: evidence for a proto-hypothalamo-retinal territory.
      Razy-Krajka, F; Brown, ER; Horie, T; Callebert, J; Sasakura, Y; Joly, JS; Kusakabe, TG; Vernier, P
      BMC biology  10  45  2012

      Show Abstract
      22642675 22642675
      The dorsal raphe modulates sensory responsiveness during arousal in zebrafish.
      Yokogawa, T; Hannan, MC; Burgess, HA
      The Journal of neuroscience : the official journal of the Society for Neuroscience  32  15205-15  2012

      Show Abstract
      23100441 23100441
      Organizational effects of oxytocin on serotonin innervation.
      Jennifer L Eaton,Laura Roache,Khanhbao N Nguyen,Bruce S Cushing,Emma Troyer,Eros Papademetriou,Mary Ann Raghanti
      Developmental psychobiology  54  2012

      Show Abstract
      21594870 21594870
      Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways.
      Serre, A; Snyder, EY; Mallet, J; Buchet, D
      Stem cells and development  21  539-53  2012

      Show Abstract
      ImmunocytochemistryHuman21561385 21561385
      Organisation and chemical neuroanatomy of the African elephant (Loxodonta africana) olfactory bulb.
      Ngwenya A, Patzke N, Ihunwo AO, Manger PR.
      Brain structure & function  216  403-16  2011

      Show Abstract
      21479949 21479949
      Synaptic connections between GABAergic elements and serotonergic terminals or projecting neurons in the ventrolateral orbital cortex.
      Huo, FQ; Chen, T; Lv, BC; Wang, J; Zhang, T; Qu, CL; Li, YQ; Tang, JS
      Cerebral cortex (New York, N.Y. : 1991)  19  1263-72  2009

      Show Abstract
      18980950 18980950
      Axonal projections originating from raphe serotonergic neurons in the developing and adult zebrafish, Danio rerio, using transgenics to visualize raphe-specific pet1 expression.
      Christina Lillesaar,Christian Stigloher,Birgit Tannhäuser,Mario F Wullimann,Laure Bally-Cuif
      The Journal of comparative neurology  512  2009

      Show Abstract
      19003874 19003874
      Source, topography and excitatory effects of GABAergic innervation in cockroach salivary glands.
      Rotte, C; Witte, J; Blenau, W; Baumann, O; Walz, B
      The Journal of experimental biology  212  126-36  2009

      Show Abstract
      19088218 19088218

      Data Sheet

      Title
      Anti-Serotonin, clone YC5/45 - Data Sheet

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies