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ABN273 | Anti-SLC22A12 Antibody

150 µL  
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      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H WB Rb Affinity Purified Polyclonal Antibody
      Catalogue NumberABN273
      DescriptionAnti-SLC22A12 Antibody
      Alternate Names
      • Solute carrier family 22 member 12
      • Organic anion transporter 4-like protein
      • Renal-specific transporter
      • RST
      • Urate anion exchanger 1
      Background InformationSolute carrier family 22 member 12 (SLC22A12) is a member of the Organic cation transporter (TC 2.A.1.19) family regulating blood urate levels by mediating saturable urate uptake by facilitating the exchange of urate against organic anions. SLC22A12 is found in kidney at the protein level. Mutations in SLC22A12 have been associated with hypouricemia renal type 1, a disorder characterized by impaired uric acid reabsorption.
      Product Information
      FormatAffinity Purified
      • Human kidney tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide and 50% glycerol.
      ApplicationThis SLC22A12 antibody is validated for use in WB for the detection of the SLC22A12 protein.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human SLC22A12.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • SLC22A12
      • URAT1
      • OATL4
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~68 kDa observed. The calculated molecular weight of this protein is 60 kDa, but can be observed at ~68 kDa due to high glycosylation. Uncharacterized bands may appear in some lysates.
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human kidney tissue lysate.

      Western Blotting Analysis: A 1:800 dilution of this antibody detected SLC22A12 1 in 30 µg of human kidney tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size150 µL
      Transport Information
      Supplemental Information