A part of MilliporeSigma

MABE927 | Anti-SAE2 Antibody, clone 7H8.1

100 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
Request Pricing
Limited AvailabilityLimited Availability
Limited Quantities Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers


      Contact Customer Service

      Click To Print This Page


      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R WB, IHC M Purified Monoclonal Antibody
      Catalogue NumberMABE927
      DescriptionAnti-SAE2 Antibody, clone 7H8.1
      Alternate Names
      • SUMO-activating enzyme subunit 2
      • Anthracycline-associated resistance ARX
      • Ubiquitin-like 1-activating enzyme E1B
      • Ubiquitin-like modifier-activating enzyme 2
      Background InformationSUMO-activating enzyme subunit 2, also known as Anthracycline-associated resistance ARX, or Ubiquitin-like 1-activating enzyme E1B, and encoded by the gene name UBA2 or SAE2 or UBLE1B, belongs to the ubiquitin-activating E1 family. SUMOs are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.
      Product Information
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      ApplicationAnti-SAE2 Antibody, clone 7H8.1 | MABE927 is an antibody against SAE2 Antibody for use in Western Blotting, Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected SAE2 in human kidney and rat testis tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human SAE2.
      ConcentrationPlease refer to lot specific datasheet.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • UBA2
      • SAE2
      • UBLE1B
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~80 kDa observed. The calculated molecular weight is 72 kDa, however SAE2 has been shown as a ~70-90 kDa band in western blots (Truong, K., et al. (2012). J. Biol. Chem. 287(51):42611-42619).
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Neuro-2a cell lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected SAE2 in 10 µg of Neuro-2a cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-SAE2, clone 7H8.1 -Q2504975 Q2504975


      Reference overviewPub Med ID
      The Journal of biological chemistry
      Truong, K; Lee, TD; Li, B; Chen, Y
      The Journal of biological chemistry 287 42611-9 2012

      Show Abstract
      23095757 23095757

      Related Products & Applications

      Related Products

      Catalog Number Description  
      ABS768 Anti-SAE2 Antibody Show Pricing & Availability

      View Gene Related Products for this Target


      Life Science Research > Antibodies and Assays > Primary Antibodies